Literature DB >> 1187722

Influence of apomorphine on brain serotonin turnover rate.

M Grabowska.   

Abstract

Apomorphine (5.0 mg/kg) accelerated the disappearance of 5-HIAA from the brain of pargylinepretreated rats as well as depletion of brain 5-HT caused by inhibition of its synthesis. The latter effect has been abolished by spiroperidol. The results obtained suggest that apomorphine increases the 5-HT turnover rate, secondary to the stimulation of central dopamine receptors.

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Year:  1975        PMID： 1187722     DOI： 10.1016/0091-3057(75)90178-1

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN： 0091-3057            Impact factor:   3.533


  8 in total

1.  Effect of nomifensine on central 5-hydroxytryptamine neurons.

Authors:  E Mogilnicka; V Klimek; K Golembiowska-Nikitin
Journal:  J Neural Transm       Date:  1977       Impact factor: 3.575

2.  Effects of morphine, physostigmine and raphe nuclei stimulation on 5-hydroxytryptamine release from the cerebral cortex of the cat.

Authors:  P Aiello-Malmberg; A Bartolini; R Bartolini; A Galli
Journal:  Br J Pharmacol       Date:  1979-04       Impact factor: 8.739

3.  Possible importance of 5-hydroxytryptamine in neuroleptic-induced catalepsy in rats [proceedings].

Authors:  C J Carter; C J Pycock
Journal:  Br J Pharmacol       Date:  1977-06       Impact factor: 8.739

4.  5,7-Dihydroxytryptamine lesions of the amygdala reduce amphetamine- and apomorphine-induced stereotyped behaviour in the rat.

Authors:  C J Carter; C J Pycock
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1980-07       Impact factor: 3.000

5.  Apomorphine in the rat nucleus accumbens: effects on the synthesis of 5-hydroxytryptamine and noradrenaline, the motor activity and the body temperature.

Authors:  M Grabowska; N E Andén
Journal:  J Neural Transm       Date:  1976       Impact factor: 3.575

Review 6.  Agonist--antagonist interaction on dopamine receptors in brain, as reflected in the rates of tyrosine and tryptophan hydroxylation.

Authors:  A Carlsson; W Kehr; M Lindqvist
Journal:  J Neural Transm       Date:  1977       Impact factor: 3.575

7.  Dopamine agonists and interaction with other neurotransmitter systems.

Authors:  J Maj
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977       Impact factor: 3.000

Review 8.  Pharmacological Insights into the Use of Apomorphine in Parkinson's Disease: Clinical Relevance.

Authors:  Manon Auffret; Sophie Drapier; Marc Vérin
Journal:  Clin Drug Investig       Date:  2018-04       Impact factor: 2.859
  8 in total

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