Literature DB >> 11872314

Amniotic fluid soluble human leukocyte antigen G is markedly decreased in offspring with neural tube defects.

Peter M Emmer1, Eric A P Steegers, Marié Jose van Lierop, Régine P M Steegers-Theunissen, Yung Way Loke, Irma Joosten.   

Abstract

Pregnancies affected by a neural tube defect show changes in thymus morphology, neonatal and maternal T-cell repertoire. Amniotic fluid levels of soluble human leukocyte antigen G (HLA-G) (an immuno-modulatory protein) were found to be significantly lower as compared to controls. This may reflect a diminished cell-mediated immunity in neural tube defects.

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Year:  2002        PMID： 11872314     DOI： 10.1016/s0378-3782(01)00236-5

Source DB:  PubMed          Journal:  Early Hum Dev        ISSN： 0378-3782            Impact factor:   2.079


  4 in total

1.  Pax1/E2a double-mutant mice develop non-lethal neural tube defects that resemble human malformations.

Authors:  Paulus H L J Joosten; Everardus J J van Zoelen; Cornelis Murre
Journal:  Transgenic Res       Date:  2005-12       Impact factor: 2.788

Review 2.  HLA-G and its role in implantation (review).

Authors:  Roumen G Roussev; Carolyn B Coulam
Journal:  J Assist Reprod Genet       Date:  2007-07-14       Impact factor: 3.412

3.  Amniotic fluid soluble human leukocyte antigen-G in term and preterm parturition, and intra-amniotic infection/inflammation.

Authors:  Juan Pedro Kusanovic; Roberto Romero; Cristiano Jodicke; Shali Mazaki-Tovi; Edi Vaisbuch; Offer Erez; Pooja Mittal; Francesca Gotsch; Tinnakorn Chaiworapongsa; Sam S Edwin; Percy Pacora; Sonia S Hassan
Journal:  J Matern Fetal Neonatal Med       Date:  2009-12

Review 4.  HLA-G/ILTs Targeted Solid Cancer Immunotherapy: Opportunities and Challenges.

Authors:  Aifen Lin; Wei-Hua Yan
Journal:  Front Immunol       Date:  2021-06-30       Impact factor: 7.561
  4 in total

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