Literature DB >> 11871379

Platelet concentrate increases bone ingrowth into porous hydroxyapatite.

Maikel A N Siebrecht1, Philippe P De Rooij, Douglas M Arm, Martin L Olsson, Per Aspenberg.   

Abstract

Platelets contain growth factors that are believed to stimulate early fracture repair. Autologous platelets can be sequestered, concentrated, and mixed with thrombin to yield a so-called autologous growth factor gel, which might enhance bone repair or bone graft incorporation. The effect of this platelet concentrate on total tissue and bone ingrowth into porous coralline hydroxyapatite was studied in a bone chamber rat model. Chambers with the platelet concentrate showed a significant increase in bone and total tissue ingrowth distance compared to untreated controls, indicating a platelet concentrate might enhance the clinical performance of porous hydroxyapatite in bone replacement.

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Year:  2002        PMID： 11871379     DOI： 10.3928/0147-7447-20020201-22

Source DB:  PubMed          Journal:  Orthopedics        ISSN： 0147-7447            Impact factor:   1.390


  9 in total

1.  No effect of platelet-rich plasma with frozen or processed bone allograft around noncemented implants.

Authors:  T B Jensen; O Rahbek; S Overgaard; K Søballe
Journal:  Int Orthop       Date:  2005-02-01       Impact factor: 3.075

2.  Autologous platelet gel and platelet-poor plasma reduce pain with total shoulder arthroplasty.

Authors:  Douglas P Zavadil; C Craig Satterlee; Jaime M Costigan; David W Holt; Valerie K Shostrom
Journal:  J Extra Corpor Technol       Date:  2007-09

Review 3.  Concise review: adipose-derived stromal vascular fraction cells and platelet-rich plasma: basic and clinical implications for tissue engineering therapies in regenerative surgery.

Authors:  Pietro Gentile; Augusto Orlandi; Maria Giovanna Scioli; Camilla Di Pasquali; Ilaria Bocchini; Valerio Cervelli
Journal:  Stem Cells Transl Med       Date:  2012-02-22       Impact factor: 6.940

4.  Histological Evaluation of Hydroxyapatite Granules with and without Platelet-Rich Plasma versus an Autologous Bone Graft: Comparative study of biomaterials used for spinal fusion in a New Zealand white rabbit model.

Authors:  Zamzuri Zakaria; Che N Z C Seman; Zunariah Buyong; Mohd A Sharifudin; Ahmad H Zulkifly; Kamarul A Khalid
Journal:  Sultan Qaboos Univ Med J       Date:  2016-11-30

5.  Anterior lumbar interbody fusion with carbon fiber cage loaded with bioceramics and platelet-rich plasma. An experimental study on pigs.

Authors:  Haisheng Li; Xuenong Zou; Qingyun Xue; Niels Egund; Martin Lind; Cody Bünger
Journal:  Eur Spine J       Date:  2004-01-17       Impact factor: 3.134

6.  No effect of autologous growth factors (AGF) around ungrafted loaded implants in dogs.

Authors:  Thomas Bo Jensen; J E Bechtold; X Chen; M Vestermark; K Søballe
Journal:  Int Orthop       Date:  2009-10-25       Impact factor: 3.075

7.  A comparative translational study: the combined use of enhanced stromal vascular fraction and platelet-rich plasma improves fat grafting maintenance in breast reconstruction.

Authors:  Pietro Gentile; Augusto Orlandi; Maria Giovanna Scioli; Camilla Di Pasquali; Ilaria Bocchini; Cristiano Beniamino Curcio; Micol Floris; Valeria Fiaschetti; Roberto Floris; Valerio Cervell
Journal:  Stem Cells Transl Med       Date:  2012-04-13       Impact factor: 6.940

Review 8.  Solid Platelet Rich Plasma in Corneal Surgery.

Authors:  Francisco Arnalich; Alejandra E Rodriguez; Alvaro Luque-Rio; Jorge L Alio
Journal:  Ophthalmol Ther       Date:  2016-05-14

9.  The Bone Regeneration Using Bone Marrow Stromal Cells with Moderate Concentration Platelet-Rich Plasma in Femoral Segmental Defect of Rats.

Authors:  Junichi Yamakawa; Junichi Hashimoto; Mitsuo Takano; Michiaki Takagi
Journal:  Open Orthop J       Date:  2017-01-30
  9 in total

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