Literature DB >> 11870787

Use of a novel erbium laser in a Yucatan minipig: a study of residual thermal damage, ablation, and wound healing as a function of pulse duration.

Edward V Ross1, Joseph R McKinlay, Francis P Sajben, Charles H Miller, David J Barnette, Kenneth J Meehan, Norak P Chhieng, Mickey J Deavers, Brian D Zelickson.   

Abstract

BACKGROUND AND
OBJECTIVE: Theoretical models show that varying pulse duration influences residual thermal damage in erbium YAG skin resurfacing. Accordingly, our objective was to compare residual thermal damage, ablation, tissue shrinkage, and wound healing between a variable pulsewidth erbium YAG laser and a popular CO2 resurfacing laser. STUDY DESIGN/
MATERIALS AND METHODS: The erbium laser delivered a typical ablative pulse (250 microseconds), followed by a heating pulse of variable duration. Pulse durations for specific coagulation depths were selected based on existing heat transfer models. The bilateral flanks of one Yucatan pig were irradiated. Eight sites were treated per group. Biopsies were performed just after treatment and 1, 3, 7, 21, and 60 days postoperatively.
RESULTS: Just after irradiation, gross examination of "cold" (without a coagulation pulse) erbium sites showed a reddish papillary dermis consistent with conventional erbium laser ablation. Two and three pass CO2 sites showed uniform surface yellowing. The longer pulsewidth ("hot") erbium groups showed only slight surface yellowing. Biopsies showed immediate thermal damage that increased with erbium pulse duration; however, actual residual thermal damage (RTD) was sometimes less than that predicted by the laser control panel. All wounds healed uneventfully by 14 days.
CONCLUSIONS: An erbium laser with a variable macropulse pulsewidth was capable of achieving RTD of up to 80 mum. Even greater RTD depths may be obtainable with future manipulations of fluence and pulse duration. Copyright 2002 Wiley-Liss, Inc.

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Year:  2002        PMID: 11870787     DOI: 10.1002/lsm.10030

Source DB:  PubMed          Journal:  Lasers Surg Med        ISSN: 0196-8092            Impact factor:   4.025


  5 in total

1.  Optical nerve identification in head and neck surgery after Er:YAG laser ablation.

Authors:  Florian Stelzle; Christian Knipfer; Bastian Bergauer; Maximilian Rohde; Werner Adler; Katja Tangermann-Gerk; Emeka Nkenke; Michael Schmidt
Journal:  Lasers Med Sci       Date:  2014-04-03       Impact factor: 3.161

2.  Effects of infrared radiation on skin photo-aging and pigmentation.

Authors:  Ju Hee Lee; Mi Ryung Roh; Kwang Hoon Lee
Journal:  Yonsei Med J       Date:  2006-08-31       Impact factor: 2.759

3.  Use of 1070 nm fiber lasers in oral surgery: preliminary ex vivo study with FBG temperature monitoring.

Authors:  Carlo Fornaini; Elisabetta Merigo; Federica Poli; Chiara Cavatorta; Jean-Paul Rocca; Stefano Selleri; Annamaria Cucinotta
Journal:  Laser Ther       Date:  2017-12-31

4.  The impact of laser ablation on optical soft tissue differentiation for tissue specific laser surgery-an experimental ex vivo study.

Authors:  Florian Stelzle; Ingo Terwey; Christian Knipfer; Werner Adler; Katja Tangermann-Gerk; Emeka Nkenke; Michael Schmidt
Journal:  J Transl Med       Date:  2012-06-15       Impact factor: 5.531

5.  Characteristics of Non-Ablative Resurfacing of Soft Tissues by Repetitive Er:YAG Laser Pulse Irradiation.

Authors:  Matjaz Lukac; Anze Zorman; Nejc Lukac; Tadej Perhavec; Blaz Tasic
Journal:  Lasers Surg Med       Date:  2021-04-01       Impact factor: 4.025

  5 in total

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