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Literature DB >> 11867097

Coumarins and gamma-pyrone derivatives from Prangos pabularia: antibacterial activity and inhibition of cytokine release.

Yukiko Tada¹, Yasuhiro Shikishima, Yoshihisa Takaishi, Hirofumi Shibata, Tomihiko Higuti, Gisho Honda, Michiho Ito, Yoshio Takeda, Olimjon K Kodzhimatov, Ozodbek Ashurmetov, Yasukazu Ohmoto.

Abstract

The n-hexane and ethyl acetate extracts of the stems and the ethyl acetate extracts of roots from Prangos pabularia afforded an gamma-pyrone derivative and furanocoumarin derivatives with three glucose and gamma-pyrone (pabularin A, B and C), along with 26 previously known compounds (18 coumarins, six terpenoids and two glycosides). Their structures were established on the basis of spectroscopic studies. Of these, 16 coumarin derivatives isolated from P. pabularia were tested for antibacterial activity and inhibition of cytokine release.

Entities: Chemical Species

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Year: 2002 PMID： 11867097 DOI： 10.1016/s0031-9422(02)00023-7

Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072

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Cited

12 in total

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Coumarins and gamma-pyrone derivatives from Prangos pabularia: antibacterial activity and inhibition of cytokine release.

1. Four new glucosides from the aerial parts of Mediasia macrophylla.

2. Anticoccidial effects of herbal extracts on Eimeria tenella infection in broiler chickens: in vitro and in vivo study.

3. Antiproliferative effects of essential oils and their major constituents in human renal adenocarcinoma and amelanotic melanoma cells.

Review 4. Astonishing diversity of natural surfactants: 7. Biologically active hemi- and monoterpenoid glycosides.

5. Isolation, cytotoxicity evaluation and HPLC-quantification of the chemical constituents from Prangos pabularia.

Review 6. Coumarin-Tetrapyrrolic Macrocycle Conjugates: Synthesis and Applications.

7. Antispasmodic effect of osthole and Prangos ferulacea extract on rat uterus smooth muscle motility.

Review 8. Imperatorin-pharmacological meaning and analytical clues: profound investigation.

9. Coumarins from Angelica lucida L.--antibacterial activities.

10. In Vitro Antioxidant and Anti-Propionibacterium acnes Activities of Cold Water, Hot Water, and Methanol Extracts, and Their Respective Ethyl Acetate Fractions, from Sanguisorba officinalis L. Roots.