Literature DB >> 11865983

Haptoglobin and malaria.

N H Hunt1, C Driussi, L Sai-Kiang.   

Abstract

Haptoglobin gene knockout mice and wild-type controls were infected with Plasmodium berghei ANKA or Plasmodium chabaudi. The peak parasitaemia and parasite burden were higher in Hp-/- mice than in Hp+/+ mice. The increase in spleen weight following malaria infection was smaller in Hp-/- mice than in Hp+/+ animals. The occurrence of cerebral malaria in P. berghei ANKA infection was not different in Hp gene knockout mice and their controls.

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Year:  2001        PMID： 11865983     DOI： 10.1179/135100001101536508

Source DB:  PubMed          Journal:  Redox Rep        ISSN： 1351-0002            Impact factor:   4.412


  8 in total

Review 1.  How malaria has affected the human genome and what human genetics can teach us about malaria.

Authors:  Dominic P Kwiatkowski
Journal:  Am J Hum Genet       Date:  2005-07-06       Impact factor: 11.025

Review 2.  Genetic analysis of cerebral malaria in the mouse model infected with Plasmodium berghei.

Authors:  Sabrina Torre; David Langlais; Philippe Gros
Journal:  Mamm Genome       Date:  2018-06-19       Impact factor: 2.957

Review 3.  Host resistance to malaria: using mouse models to explore the host response.

Authors:  Rhea Longley; Clare Smith; Anny Fortin; Joanne Berghout; Brendan McMorran; Gaétan Burgio; Simon Foote; Philippe Gros
Journal:  Mamm Genome       Date:  2010-11-30       Impact factor: 2.957

4.  The haptoglobin 2-2 genotype is associated with a reduced incidence of Plasmodium falciparum malaria in children on the coast of Kenya.

Authors:  Sarah H Atkinson; Tabitha W Mwangi; Sophie M Uyoga; Edna Ogada; Alex W Macharia; Kevin Marsh; Andrew M Prentice; Thomas N Williams
Journal:  Clin Infect Dis       Date:  2007-02-07       Impact factor: 9.079

5.  Epistasis between the haptoglobin common variant and α+thalassemia influences risk of severe malaria in Kenyan children.

Authors:  Sarah H Atkinson; Sophie M Uyoga; Emily Nyatichi; Alex W Macharia; Gideon Nyutu; Carolyne Ndila; Dominic P Kwiatkowski; Kirk A Rockett; Thomas N Williams
Journal:  Blood       Date:  2014-01-29       Impact factor: 22.113

6.  Proteomics mapping of cord blood identifies haptoglobin "switch-on" pattern as biomarker of early-onset neonatal sepsis in preterm newborns.

Authors:  Catalin S Buhimschi; Vineet Bhandari; Antonette T Dulay; Unzila A Nayeri; Sonya S Abdel-Razeq; Christian M Pettker; Stephen Thung; Guomao Zhao; Yiping W Han; Matthew Bizzarro; Irina A Buhimschi
Journal:  PLoS One       Date:  2011-10-10       Impact factor: 3.240

7.  Identification of circulating biomarkers in sera of Plasmodium knowlesi-infected malaria patients--comparison against Plasmodium vivax infection.

Authors:  Yeng Chen; Choon K Chan; Jesinda P Kerishnan; Yee L Lau; Yin-Ling Wong; Subash Cb Gopinath
Journal:  BMC Infect Dis       Date:  2015-02-06       Impact factor: 3.090

8.  Haplotype association between haptoglobin (Hp2) and Hp promoter SNP (A-61C) may explain previous controversy of haptoglobin and malaria protection.

Authors:  Sharon E Cox; Conor Doherty; Sarah H Atkinson; Chidi V Nweneka; Anthony J C Fulford; Hala Ghattas; Kirk A Rockett; Dominic P Kwiatkowski; Andrew M Prentice
Journal:  PLoS One       Date:  2007-04-11       Impact factor: 3.240
  8 in total

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