| Literature DB >> 11865316 |
M G Yakobson1, A R Antonov, A V Golovatyuk, A V Efremov, A L Markel', G S Yakobson.
Abstract
Plasma, lymph and myocardial Fe(2+) contents and blood antioxidant activity were studied in hypertensive NISAG and normotensive Wistar rats with experimental myocardial infarction. In hypertensive rats, iron levels in plasma, lymph and myocardial tissue were increased throughout the experiment. In both strains iron content in the plasma during experimental myocardial infarction negatively correlated with blood antioxidant activity. In hypertensive NISAG rats this correlation persisted also during recovery. This attests to prooxidant effect of Fe(2+) aggravating the course of myocardial infarction in NISAG rats.Entities:
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Year: 2001 PMID： 11865316 DOI： 10.1023/a:1017900121039
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804