Literature DB >> 11864880

Corneal electrolysis for recurrence of corneal stromal dystrophy after keratoplasty.

Y Mashima1, M Kawai, M Yamada.   

Abstract

AIMS: To evaluate corneal electrolysis as a treatment for recurrent diffuse corneal opacities at the host-graft interface of the stroma or at the subepithelial region in two types of granular corneal dystrophy (GCD).
METHODS: Recurrence developed at the host-graft interface of the stroma after lamellar keratoplasty in a patient with Avellino corneal dystrophy (ACD). At surgery, the deep aspect of the graft in this patient was partially separated from host tissue to expose the deposits, with one third of the host-graft junction left intact. The graft was everted, and electrolysis was applied directly to remove the deposits attached to both surfaces of the host and the graft. Then the graft was returned to its place and sutured. In two patients with homozygous ACD and one patient with the superficial variant of GCD, diffuse subepithelial opacities developed following penetrating keratoplasty. Electrolysis was applied directly to the corneal surface.
RESULTS: Deposits at the host-graft interface of the stroma and in the subepithelial region disappeared following treatment, and vision recovered in all patients.
CONCLUSIONS: This method is a simple, easy, and inexpensive way to remove deposits that recur after lamellar or penetrating keratoplasty.

Entities:  

Mesh:

Year:  2002        PMID: 11864880      PMCID: PMC1771064          DOI: 10.1136/bjo.86.3.273

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  11 in total

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2.  A novel mutation at codon 124 (R124L) in the BIGH3 gene is associated with a superficial variant of granular corneal dystrophy.

Authors:  Y Mashima; Y Nakamura; K Noda; M Konishi; M Yamada; J Kudoh; N Shimizu
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4.  Varied appearance of cornea of patients with corneal dystrophy associated with R124H mutation in the BIGH3 gene.

Authors:  M Konishi; M Yamada; Y Nakamura; Y Mashima
Journal:  Cornea       Date:  1999-07       Impact factor: 2.651

5.  Kerato-epithelin mutations in four 5q31-linked corneal dystrophies.

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7.  Granular corneal dystrophy. Visual results and pattern of recurrence after lamellar or penetrating keratoplasty.

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8.  Recurrent granular corneal dystrophy.

Authors:  J C Stuart; M L Mund; T Iwamoto; R C Troutman; H White; A G DeVoe
Journal:  Am J Ophthalmol       Date:  1975-01       Impact factor: 5.258

9.  Severe form of juvenile corneal stromal dystrophy with homozygous R124H mutation in the keratoepithelin gene in five Japanese patients.

Authors:  Y Mashima; M Konishi; Y Nakamura; Y Imamura; M Yamada; T Ogata; J Kudoh; N Shimizu
Journal:  Br J Ophthalmol       Date:  1998-11       Impact factor: 4.638

10.  Phototherapeutic keratectomy for granular and lattice corneal dystrophies at 1.5 to 4 years.

Authors:  B A Nassaralla; J Garbus; P J McDonnell
Journal:  J Refract Surg       Date:  1996 Nov-Dec       Impact factor: 3.573

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  2 in total

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