| Literature DB >> 11864763 |
Swati Biswas1, T Murugesan, Sanghamitra Sinha, Kuntal Maiti, Jiaur Rahaman Gayen, M Pal, B P Saha.
Abstract
The antidiarrhoeal activity of the methanol extract of the dried seeds of Strychnos potatorum (MESP) has been evaluated out in rats using different models (castor oil-induced diarrhoea, effects on gastrointestinal motility and on PGE(2)-induced gastric enteropooling. MESP (100, 200 and 400 mg/kg, p.o.) significantly (P<0.001) inhibited the frequency of defaecation and reduced the wetness of faecal droppings in castor oil-induced diarrhoea, decreased the propulsion of charcoal meal through the gastrointestinal tract, and also reduced the PGE(2)-induced enteropooling.Entities:
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Year: 2002 PMID: 11864763 DOI: 10.1016/s0367-326x(01)00368-9
Source DB: PubMed Journal: Fitoterapia ISSN: 0367-326X Impact factor: 2.882