| Literature DB >> 11864595 |
Abstract
CtBP family proteins are conserved among vertebrates and invertebrates and function as transcriptional corepressors. They repress transcription in a histone deacetylase-dependent or -independent manner. CtBPs play important roles during development and oncogenesis. In this review, their unusual properties, the mechanisms of transcriptional repression, regulation, and their biological functions are discussed.Entities:
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Year: 2002 PMID: 11864595 DOI: 10.1016/s1097-2765(02)00443-4
Source DB: PubMed Journal: Mol Cell ISSN: 1097-2765 Impact factor: 17.970