Literature DB >> 11864595

CtBP, an unconventional transcriptional corepressor in development and oncogenesis.

G Chinnadurai1.   

Abstract

CtBP family proteins are conserved among vertebrates and invertebrates and function as transcriptional corepressors. They repress transcription in a histone deacetylase-dependent or -independent manner. CtBPs play important roles during development and oncogenesis. In this review, their unusual properties, the mechanisms of transcriptional repression, regulation, and their biological functions are discussed.

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Year:  2002        PMID: 11864595     DOI: 10.1016/s1097-2765(02)00443-4

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  213 in total

1.  Smad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription.

Authors:  Xia Lin; Yao-Yun Liang; Baohua Sun; Min Liang; Yujiang Shi; F Charles Brunicardi; Yang Shi; Xin-Hua Feng
Journal:  Mol Cell Biol       Date:  2003-12       Impact factor: 4.272

2.  Functional similarity of Knirps CtBP-dependent and CtBP-independent transcriptional repressor activities.

Authors:  Jae-Ryeon Ryu; David N Arnosti
Journal:  Nucleic Acids Res       Date:  2003-08-01       Impact factor: 16.971

3.  CtBP contributes quantitatively to Knirps repression activity in an NAD binding-dependent manner.

Authors:  Montserrat Sutrias-Grau; David N Arnosti
Journal:  Mol Cell Biol       Date:  2004-07       Impact factor: 4.272

4.  Expression of an E1A/E7 chimeric protein sensitizes tumor cells to killing by activated macrophages but not NK cells.

Authors:  Tanya A Miura; Han Li; Kristin Morris; Sharon Ryan; Kristine Hembre; James L Cook; John M Routes
Journal:  J Virol       Date:  2004-05       Impact factor: 5.103

Review 5.  Evolutionary functional analysis and molecular regulation of the ZEB transcription factors.

Authors:  Alexander Gheldof; Paco Hulpiau; Frans van Roy; Bram De Craene; Geert Berx
Journal:  Cell Mol Life Sci       Date:  2012-02-21       Impact factor: 9.261

6.  NAD+-dependent deacetylase Hst1p controls biosynthesis and cellular NAD+ levels in Saccharomyces cerevisiae.

Authors:  Antonio Bedalov; Maki Hirao; Jeffrey Posakony; Melisa Nelson; Julian A Simon
Journal:  Mol Cell Biol       Date:  2003-10       Impact factor: 4.272

7.  Strategic attack on host cell gene expression during adenovirus infection.

Authors:  Hongxing Zhao; Fredrik Granberg; Ludmila Elfineh; Ulf Pettersson; Catharina Svensson
Journal:  J Virol       Date:  2003-10       Impact factor: 5.103

8.  High expression and prognostic role of CAP1 and CtBP2 in breast carcinoma: associated with E-cadherin and cell proliferation.

Authors:  Xiancheng Liu; Ninghua Yao; Jing Qian; Huiwei Huang
Journal:  Med Oncol       Date:  2014-02-13       Impact factor: 3.064

9.  Role of transcriptional corepressor CtBP1 in prostate cancer progression.

Authors:  Rui Wang; Irfan A Asangani; Balabhadrapatruni V S K Chakravarthi; Bushra Ateeq; Robert J Lonigro; Qi Cao; Ram-Shankar Mani; Daniel F Camacho; Natalie McGregor; Taibriana E W Schumann; Xiaojun Jing; Radhika Menawat; Scott A Tomlins; Heng Zheng; Arie P Otte; Rohit Mehra; Javed Siddiqui; Saravana M Dhanasekaran; Mukesh K Nyati; Kenneth J Pienta; Nallasivam Palanisamy; Lakshmi P Kunju; Mark A Rubin; Arul M Chinnaiyan; Sooryanarayana Varambally
Journal:  Neoplasia       Date:  2012-10       Impact factor: 5.715

10.  Effect of estrogen receptor α binding on functional DNA methylation in breast cancer.

Authors:  Matthew Ung; Xiaotu Ma; Kevin C Johnson; Brock C Christensen; Chao Cheng
Journal:  Epigenetics       Date:  2014-01-16       Impact factor: 4.528

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