| Literature DB >> 11864594 |
Stavros Lomvardas1, Dimitris Thanos.
Abstract
How the transcriptional apparatus gains access to and subsequently opens compacted chromatin has remained a mystery. Now in this issue of Molecular Cell, Zaret and coworkers show that chromatin opening in vitro is not mediated by the classical chromatin remodeling machines but instead occurs through specific transcription factor-histone interactions.Mesh:
Substances:
Year: 2002 PMID: 11864594 DOI: 10.1016/s1097-2765(02)00463-x
Source DB: PubMed Journal: Mol Cell ISSN: 1097-2765 Impact factor: 17.970