| Literature DB >> 11863265 |
Carl F Marrs, Lixin Zhang, Patricia Tallman, Shannon D Manning, Patricia Somsel1, Paul Raz1, Raul Colodner1, Maria E Jantunen1, Anja Siitonen1, Harri Saxen1, Betsy Foxman.
Abstract
A total of 868 isolates was screened from seven different collections of organisms from previous studies - pyelonephritis in children aged 1-24 months; first, second and recurring urinary tract infection (UTI) in women aged 18-39 years; UTI in women aged 40-65 years and peri-urethral and faecal isolates from women aged 18-39 years - for the presence of 10 potential Escherichia coli UTI virulence genes. Previously reported differences between the frequency of these genes in UTI compared with faecal isolates were confirmed and extended. A single virulence signature (strains containing aer, kpsMT, ompT, fim and papGAD) occurred in 29% of the pyelonephritic isolates, but in no more than 11% of the other collections. Peri-urethral isolates were found to have frequencies of these 10 genes that differed from those found for both UTI and faecal isolates.Entities:
Mesh：
Year: 2002 PMID： 11863265 DOI： 10.1099/0022-1317-51-2-138
Source DB: PubMed Journal: J Med Microbiol ISSN： 0022-2615 Impact factor: 2.472