Literature DB >> 11863154

Effects of dental local anaesthetics in cardiac transplant recipients.

J G Meechan1, G Parry, D T Rattray, J M Thomason.   

Abstract

OBJECTIVE: To investigate the cardiovascular responses of cardiac transplant recipients to dental local anaesthetic solutions with and without epinephrine (adrenaline).
MATERIALS AND METHODS: A clinical study employing 30 patients (20 cardiac transplant recipients and ten healthy) awaiting gingival or minor oral surgery under local anaesthesia receiving either 4.4 ml lidocaine (lignocaine) with 1:80,000 epinephrine or 4.4 ml 3% prilocaine with 0.031 U/ml felypressin.
RESULTS: Cardiac transplant patients experienced a significant tachycardia 10 minutes after injection of the epinephrine-containing solution. No significant change in heart rate was detected after the injection of an epinephrine-free solution. Blood pressure was not affected. Periodontal surgery did not affect the responses to the local anaesthetics in the transplant recipients.
CONCLUSIONS: The cardiovascular response to dental local anaesthesia in cardiac transplant recipients is governed by the solution injected.

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Year:  2002        PMID: 11863154     DOI: 10.1038/sj.bdj.4801323

Source DB:  PubMed          Journal:  Br Dent J        ISSN: 0007-0610            Impact factor:   1.626


  10 in total

1.  Efficacy and safety of intraseptal and periodontal ligament anesthesia achieved by computer-controlled articaine + epinephrine delivery: a dose-finding study.

Authors:  Vladimir Biocanin; Bozidar Brkovic; Biljana Milicic; Dragica Stojic
Journal:  Clin Oral Investig       Date:  2012-04-25       Impact factor: 3.573

2.  Cardiovascular alterations after injection of 2% lidocaine with norepinephrine 1:50,000 (xylestesin) in rats.

Authors:  Fatima Neves Faraco; Paschoal Laercio Armonia; Stanley F Malamed
Journal:  Anesth Prog       Date:  2007

3.  Evaluation of the haemodynamic and metabolic effects of local anaesthetic agent in routine dental extractions.

Authors:  V I Akinmoladun; V N Okoje; O M Akinosun; A O Adisa; O C Uchendu
Journal:  J Maxillofac Oral Surg       Date:  2012-12-02

4.  Comparison of epinephrine and felypressin pressure effects in 1K1C hypertensive rats treated or not with atenolol.

Authors:  Camila A Fleury; Vagner C Andreo; Pedro C Lomba; Thiago J Dionísio; Sandra L Amaral; Carlos F Santos; Flávio A Faria
Journal:  J Anesth       Date:  2014-06-25       Impact factor: 2.078

5.  Influence of local anesthetics with or without epinephrine 1/80000 on blood pressure and heart rate: A randomized double-blind experimental clinical trial.

Authors:  Mohammad Ketabi; Mehrnaz Sadighi Shamami; Maryam Alaie; Mehrnoosh Sadighi Shamami
Journal:  Dent Res J (Isfahan)       Date:  2012-07

6.  Comparing hemodynamic and glycemic response to local anesthesia with epinephrine and without epinephrine in patients undergoing tooth extractions.

Authors:  Paramjot Kaur; Rashi Bahl; Sameer Kaura; Sumit Bansal
Journal:  Natl J Maxillofac Surg       Date:  2016 Jul-Dec

7.  Comparative evaluation of the efficacy, safety, and hemostatic effect of 2% lidocaine with various concentrations of epinephrine.

Authors:  Myong-Hwan Karm; Minyoung Kim; Fiona D Park; Kwang-Suk Seo; Hyun Jeong Kim
Journal:  J Dent Anesth Pain Med       Date:  2018-06-29

8.  Locoregional anesthesia for dental treatment in cardiac patients: a comparative study of 2% plain lidocaine and 2% lidocaine with epinephrine (1:100,000).

Authors:  Alessandra Batistela Laragnoit; Ricardo Simões Neves; Itamara Lúcia Itagiba Neves; Joaquim Edson Vieira
Journal:  Clinics (Sao Paulo)       Date:  2009       Impact factor: 2.365

9.  Hemodynamic changes following injection of local anesthetics with different concentrations of epinephrine during simple tooth extraction: A prospective randomized clinical trial.

Authors:  Nedal Abu-Mostafa; Fatimah Al-Showaikhat; Fatimah Al-Shubbar; Kawther Al-Zawad; Fatimah Al-Zawad
Journal:  J Clin Exp Dent       Date:  2015-10-01

Review 10.  Use of anesthetics associated to vasoconstrictors for dentistry in patients with cardiopathies. Review of the literature published in the last decade.

Authors:  María A Serrera Figallo; Rocío T Velázquez Cayón; Daniel Torres Lagares; Jose R Corcuera Flores; Guillermo Machuca Portillo
Journal:  J Clin Exp Dent       Date:  2012-04-01
  10 in total

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