C H Kim1, S H Paek, I A Park, J G Chi, D G Kim. 1. Department of Neurosurgery, Clinical Research Institute, Seoul National University Hospital and College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-744, Korea.
Abstract
BACKGROUND: The authors report three cases of cerebral germinoma that occurred in young adults with unusual presentation. METHOD: All three patients presented with hemiparesis and were treated at Seoul National University. A histological diagnosis of germinoma was made by a stereotactic biopsy in all three cases. FINDINGS: Magnetic resonance (MR) images showed that their tumors were located in the internal capsule and thalamus, and were associated with ipsilateral cerebral hemisphere and brain stem atrophy. The hemiparesis slowly progressed and this was accompanied by a haemorrhagic cyst in each patient. INTERPRETATION: Clinical diagnosis was not easy because of the unusual clinical presentations and atypical MR imaging findings. It is suggested that cerebral germinoma should be included in the differential diagnosis of a haemorrhagic mass which is associated with cerebral atrophy in the thalamus, basal ganglia, or internal capsule, especially in adolescents or young adults.
BACKGROUND: The authors report three cases of cerebral germinoma that occurred in young adults with unusual presentation. METHOD: All three patients presented with hemiparesis and were treated at Seoul National University. A histological diagnosis of germinoma was made by a stereotactic biopsy in all three cases. FINDINGS: Magnetic resonance (MR) images showed that their tumors were located in the internal capsule and thalamus, and were associated with ipsilateral cerebral hemisphere and brain stem atrophy. The hemiparesis slowly progressed and this was accompanied by a haemorrhagic cyst in each patient. INTERPRETATION: Clinical diagnosis was not easy because of the unusual clinical presentations and atypical MR imaging findings. It is suggested that cerebral germinoma should be included in the differential diagnosis of a haemorrhagic mass which is associated with cerebral atrophy in the thalamus, basal ganglia, or internal capsule, especially in adolescents or young adults.
Authors: Rodrigo V Ozelame; Manohar Shroff; Bradley Wood; Eric Bouffet; Ute Bartels; James M Drake; Cynthia Hawkins; Susan Blaser Journal: Pediatr Radiol Date: 2006-02-04
Authors: Jeehun Lee; Bo Lyun Lee; Keon Hee Yoo; Ki Woong Sung; Hong Hoe Koo; Su Jin Lee; Joon Young Choi; Kyung-Han Lee; Jung Il Lee; Hyung-Jin Shin; Ji Hye Kim; Yeon Lim Suh; Ke Hyang Lee; Munhyang Lee Journal: Childs Nerv Syst Date: 2008-08-19 Impact factor: 1.475
Authors: S Sartori; A M Laverda; M Calderone; C Carollo; E Viscardi; R Faggin; G Perilongo Journal: Childs Nerv Syst Date: 2007-07-03 Impact factor: 1.475