Literature DB >> 11860562

Juvenile acanthosis nigricans and insulin resistance.

Trinh Hermanns-Lê1, Jean François Hermanns, Gérald E Piérard.   

Abstract

Acanthosis nigricans in obese adolescents is frequently associated with hyperinsulinemia and insulin resistance. We report three cases of this condition. In the early stage the skin lesions appeared to be erythematous and pruritic, mimicking an inflammatory dermatitis. Dietary control and oral metformin hydrochloride markedly improved the lesions. Topical calcipotriol may also help to control the skin condition.

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Year:  2002        PMID: 11860562     DOI: 10.1046/j.1525-1470.2002.00013.x

Source DB:  PubMed          Journal:  Pediatr Dermatol        ISSN: 0736-8046            Impact factor:   1.588


  8 in total

1.  Recovery of acanthosis nigricans under prolonged metformin treatment in an adolescent with normal weight.

Authors:  M Wasniewska; T Arrigo; G Crisafulli; F Lombardo; M F Messina; G Salzano; M Valenzise; F De Luca
Journal:  J Endocrinol Invest       Date:  2009-05-05       Impact factor: 4.256

Review 2.  Nonalcoholic steatohepatitis in children.

Authors:  Eve A Roberts
Journal:  Curr Gastroenterol Rep       Date:  2003-06

Review 3.  Acanthosis nigricans in obese adolescents: prevalence, impact, and management challenges.

Authors:  Hak Yung Ng
Journal:  Adolesc Health Med Ther       Date:  2016-12-16

Review 4.  A Molecular Perspective on the Potential Benefits of Metformin for the Treatment of Inflammatory Skin Disorders.

Authors:  Ji-Eun Chang; Min Sik Choi
Journal:  Int J Mol Sci       Date:  2020-11-25       Impact factor: 5.923

5.  The skin landscape in diabetes mellitus. Focus on dermocosmetic management.

Authors:  Gérald E Piérard; Sophie Seité; Trinh Hermanns-Lê; Philippe Delvenne; André Scheen; Claudine Piérard-Franchimont
Journal:  Clin Cosmet Investig Dermatol       Date:  2013-05-15

6.  Co-occurrence of acanthosis nigricans and bladder adenocarcinoma - case report.

Authors:  Karolina Olek-Hrab; Wojciech Silny; Ryszard Zaba; Agnieszka Osmola-Mańkowska; Małgorzata Mackiewicz-Wysocka; Aleksandra Dańczak-Pazdrowska
Journal:  Contemp Oncol (Pozn)       Date:  2013-06-28

7.  Metformin - For the dermatologist.

Authors:  Aditya Kumar Bubna
Journal:  Indian J Pharmacol       Date:  2016 Jan-Feb       Impact factor: 1.200

8.  Acanthosis nigricans in the knuckles: An early, accessible, straightforward, and sensitive clinical tool to predict insulin resistance.

Authors:  Gloria González-Saldivar; René Rodríguez-Gutiérrez; Andrés Marcelo Treviño-Alvarez; Minerva Gómez-Flores; Juan Montes-Villarreal; Neri Alejandro Álvarez-Villalobos; Anasofía Elizondo-Plazas; Alejandro Salcido-Montenegro; Jorge Ocampo-Candiani; José Gerardo González-González
Journal:  Dermatoendocrinol       Date:  2018-05-21
  8 in total

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