Literature DB >> 11859008

Assamicin I and II, novel triterpenoid saponins with insulin-like activity from Aesculus assamica Griff.

Takashi Sakurai1, Toshio Nishimura, Noboru Otake, Yao Xinsheng, Keiichi Abe, Mitsuhiro Zeida, Hiromichi Nagasawa, Shohei Sakuda.   

Abstract

Two novel triterpenoid saponins with insulin-like activity, termed assamicin I and II, were isolated from the roots of Aesculus assamica Griff. and their structures were characterized as 1 and 2, respectively. They inhibited release of free fatty acids from epinephrine-treated rat adipocytes and enhanced glucose uptake into 3T3-L1 adipocytes.

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Year:  2002        PMID: 11859008     DOI: 10.1016/s0960-894x(02)00019-7

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  The role of lipid and carbohydrate digestive enzyme inhibitors in the management of obesity: a review of current and emerging therapeutic agents.

Authors:  Sonia A Tucci; Emma J Boyland; Jason Cg Halford
Journal:  Diabetes Metab Syndr Obes       Date:  2010-05-10       Impact factor: 3.168

Review 2.  Tissue Culture Response of Ornamental and Medicinal Aesculus Species-A Review.

Authors:  Snežana Zdravković-Korać; Jelena Milojević; Maja Belić; Dušica Ćalić
Journal:  Plants (Basel)       Date:  2022-01-20
  2 in total

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