| Literature DB >> 11858657 |
S Watanabe1, H Hirai, Y Kato, H Nishida, T Saito, N Yoshikawa, T Parkinson, Y Kojima.
Abstract
A new antifungal agent, CJ-19,784 (I), was isolated from the fermentation broth of a fungus, Acanthostigmella sp. CL12082. Based on spectroscopic analyses, structure of I was determined to be 3'-bromo-2',5-dihydroxy-3,7,8-trimethoxy-flavone. Compound I inhibits the growth of pathogenic fungi, Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus with IC50 values of 0.11, 20 and 0.54 microg/ml, respectively.Entities:
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Year: 2001 PMID： 11858657 DOI： 10.7164/antibiotics.54.1031
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649