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Literature DB >> 11857803

Conditional allele of mdm2 which encodes a p53 inhibitor.

Jason D Grier¹, Wen Yan, Guillermina Lozano.

Abstract

Entities: Gene

Mesh：

Substances：

Year: 2002 PMID： 11857803 DOI： 10.1002/gene.10066

Source DB: PubMed Journal: Genesis ISSN： 1526-954X Impact factor: 2.487

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Cited

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27 in total

1. Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development.

Authors: Shunbin Xiong; Carolyn S Van Pelt; Ana C Elizondo-Fraire; Geng Liu; Guillermina Lozano
Journal: Proc Natl Acad Sci U S A Date: 2006-02-21 Impact factor: 11.205

2. p53 pathway is involved in cell competition during mouse embryogenesis.

Authors: Guoxin Zhang; Yinyin Xie; Ying Zhou; Cong Xiang; Lai Chen; Chenxi Zhang; Xiaoshuang Hou; Jiong Chen; Hui Zong; Geng Liu
Journal: Proc Natl Acad Sci U S A Date: 2017-01-03 Impact factor: 11.205

3. Aberrant activation of p53 due to loss of MDM2 or MDMX causes early lens dysmorphogenesis.

Authors: Yiwei Zhang; Xin Zhang; Hua Lu
Journal: Dev Biol Date: 2014-09-28 Impact factor: 3.582

4. The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes.

Authors: Margot E Bowen; Jacob McClendon; Hannah K Long; Aryo Sorayya; Jeanine L Van Nostrand; Joanna Wysocka; Laura D Attardi
Journal: Dev Cell Date: 2019-06-06 Impact factor: 12.270

Conditional allele of mdm2 which encodes a p53 inhibitor.

1. Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development.

2. p53 pathway is involved in cell competition during mouse embryogenesis.

3. Aberrant activation of p53 due to loss of MDM2 or MDMX causes early lens dysmorphogenesis.

4. The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes.

5. Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders.

6. Murine Double Minute-2 Prevents p53-Overactivation-Related Cell Death (Podoptosis) of Podocytes.

7. p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo.

8. Using Mouse Models to Explore MDM-p53 Signaling in Development, Cell Growth, and Tumorigenesis.

9. Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo.

10. Mdm4 loss in the intestinal epithelium leads to compartmentalized cell death but no tissue abnormalities.