Literature DB >> 11856300

The structure of the carbohydrate backbone of the lipopolysaccharide from Acinetobacter baumannii strain ATCC 19606.

Evgeny V Vinogradov1, Jens Ø Duus, Helmut Brade, Otto Holst.   

Abstract

The chemical structure of the phosphorylated carbohydrate backbone of the lipopolysaccharide (LPS) from Acinetobacter baumannii strain ATCC 19606 was investigated by chemical analysis and NMR spectroscopy of oligosaccharides obtained after deacylation or mild acid hydrolysis. From the combined information the following carbohydrate backbones can be deduced: where R1 = H and R2 = alpha-Glcp-(1-->2)-beta-Glcp-(1-->4)-beta-Glcp-(1-->4)-beta-Glcp-(1 as major and R1 = Ac and R2 = H as minor products. All monosaccharides are d-configured. Also, smaller oligosaccharide phosphates were identified that are thought to represent degradation products of the above structures.

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Year:  2002        PMID: 11856300     DOI: 10.1046/j.0014-2956.2001.02647.x

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN: 0014-2956


  18 in total

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Authors:  Ge Zhang; Vadim Baidin; Karanbir S Pahil; Eileen Moison; David Tomasek; Nitya S Ramadoss; Arnab K Chatterjee; Case W McNamara; Travis S Young; Peter G Schultz; Timothy C Meredith; Daniel Kahne
Journal:  Proc Natl Acad Sci U S A       Date:  2018-05-07       Impact factor: 11.205

2.  Characterization of Antigenic Oligosaccharides from Gram-Negative Bacteria via Activated Electron Photodetachment Mass Spectrometry.

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Journal:  Anal Chem       Date:  2019-03-15       Impact factor: 6.986

3.  Activity of cecropin A-melittin hybrid peptides against colistin-resistant clinical strains of Acinetobacter baumannii: molecular basis for the differential mechanisms of action.

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Journal:  Antimicrob Agents Chemother       Date:  2006-04       Impact factor: 5.191

Review 4.  Pathogenic Acinetobacter: from the Cell Surface to Infinity and Beyond.

Authors:  Brent S Weber; Christian M Harding; Mario F Feldman
Journal:  J Bacteriol       Date:  2015-12-28       Impact factor: 3.490

5.  Colistin resistance in Acinetobacter baumannii is mediated by complete loss of lipopolysaccharide production.

Authors:  Jennifer H Moffatt; Marina Harper; Paul Harrison; John D F Hale; Evgeny Vinogradov; Torsten Seemann; Rebekah Henry; Bethany Crane; Frank St Michael; Andrew D Cox; Ben Adler; Roger L Nation; Jian Li; John D Boyce
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6.  Identification and characterization of a glycosyltransferase involved in Acinetobacter baumannii lipopolysaccharide core biosynthesis.

Authors:  Nicole R Luke; Shauna L Sauberan; Thomas A Russo; Janet M Beanan; Ruth Olson; Thomas W Loehfelm; Andrew D Cox; Frank St Michael; Evgeny V Vinogradov; Anthony A Campagnari
Journal:  Infect Immun       Date:  2010-03-01       Impact factor: 3.441

7.  Top-Down Characterization of Lipooligosaccharides from Antibiotic-Resistant Bacteria.

Authors:  Dustin R Klein; Matthew J Powers; M Stephen Trent; Jennifer S Brodbelt
Journal:  Anal Chem       Date:  2019-07-26       Impact factor: 6.986

8.  Structure and immunogenicity of the rough-type lipopolysaccharide from the periodontal pathogen Tannerella forsythia.

Authors:  Gerald Posch; Oleh Andrukhov; Evgeny Vinogradov; Buko Lindner; Paul Messner; Otto Holst; Christina Schäffer
Journal:  Clin Vaccine Immunol       Date:  2013-04-24

Review 9.  Expanding the paradigm for the outer membrane: Acinetobacter baumannii in the absence of endotoxin.

Authors:  Matthew Joseph Powers; M Stephen Trent
Journal:  Mol Microbiol       Date:  2017-11-20       Impact factor: 3.501

10.  Diversity in the major polysaccharide antigen of Acinetobacter baumannii assessed by DNA sequencing, and development of a molecular serotyping scheme.

Authors:  Dalong Hu; Bin Liu; Lenie Dijkshoorn; Lei Wang; Peter R Reeves
Journal:  PLoS One       Date:  2013-07-29       Impact factor: 3.240

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