Literature DB >> 1185335

Myelofibrosis in children with chronic renal insufficiency.

N Schlackman, A A Green, J L Naiman.   

Abstract

During investigation of splenomegaly in a boy with chronic renal failure and osteodystrophy, bone marrow aspirates resulted in "dry taps," whereas biopsied material provided evidence that the marrow had been replaced by fibrous tissue. In a study of six other children with chronic renal failure, similar changes were observed. These findings suggest that the anemia of chronic renal failure may in part be a result of myelofibrosis, and the resulting reduction of functional bone marrow may limit the tolerance to immunosuppressive agents in patients who undergo renal transplantation.

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Year:  1975        PMID： 1185335     DOI： 10.1016/s0022-3476(75)80294-0

Source DB:  PubMed          Journal:  J Pediatr        ISSN： 0022-3476            Impact factor:   4.406


  3 in total

1.  Paediatric idiopathic myelofibrosis.

Authors:  Annapurna Saksena; Prerna Arora; Nita Khurana; G R Sethi; Tejinder Singh
Journal:  Indian J Hematol Blood Transfus       Date:  2014-07-02       Impact factor: 0.900

2.  Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice.

Authors:  Inga Hofmann; Mitchell J Geer; Timo Vögtle; Andrew Crispin; Dean R Campagna; Alastair Barr; Monica L Calicchio; Silke Heising; Johanna P van Geffen; Marijke J E Kuijpers; Johan W M Heemskerk; Johannes A Eble; Klaus Schmitz-Abe; Esther A Obeng; Michael Douglas; Kathleen Freson; Corinne Pondarré; Rémi Favier; Gavin E Jarvis; Kyriacos Markianos; Ernest Turro; Willem H Ouwehand; Alexandra Mazharian; Mark D Fleming; Yotis A Senis
Journal:  Blood       Date:  2018-06-13       Impact factor: 22.113

3.  Hyperparathyroidism and anemia in chronic renal failure.

Authors:  D F Geary; R S Fennell; R C Braylan; A Iravani; E H Garin; G A Richard
Journal:  Eur J Pediatr       Date:  1982-12       Impact factor: 3.183
  3 in total

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