| Literature DB >> 11853284 |
N Bunyaratavej1, K M Chan, N Subramanian.
Abstract
Hyaluronic acid is a component of synovial fluid, in osteoarthritis (OA) and shows a change of property of hyaluronic acid especially its viscoelasticity causing degradation of the cartilage. Injection of hyaluronic acid into OA of the knee (Hyalgan 2 ml/wk for 4 doses) in international multicentres gave dramatic responses: decreased pain, increased mobility of the joint after 49 days of injections compared to a placebo (2 ml of normal saline) p<0.01.Entities:
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Year: 2001 PMID: 11853284
Source DB: PubMed Journal: J Med Assoc Thai ISSN: 0125-2208