BACKGROUND: The effect of breast-feeding on the concentration of nitric oxide (NO) in milk was investigated in lactating mothers. METHODS: Breast milk specimens were obtained from 45 lactating women after normal delivery on postpartum days 1, 2, 3, 4 and 5. The subjects were divided into three groups: group 1, breast-feeding only; group 2, mixed feeding (breast milk by manual expression and additional formula feeds); and group 3, formula feeding only. Milk NO concentration was measured as the sum of nitrite and nitrate using the Griess reaction. RESULTS: The highest mean milk NO concentration was on day 4 in all groups, but the peak value in group 3 was significantly lower (P<0.0001) than in other groups. The milk NO concentrations of group 1 were significantly greater than those of groups 2 and 3. CONCLUSIONS: We conclude that breast-feeding increases the concentration of NO in milk.
BACKGROUND: The effect of breast-feeding on the concentration of nitric oxide (NO) in milk was investigated in lactating mothers. METHODS: Breast milk specimens were obtained from 45 lactating women after normal delivery on postpartum days 1, 2, 3, 4 and 5. The subjects were divided into three groups: group 1, breast-feeding only; group 2, mixed feeding (breast milk by manual expression and additional formula feeds); and group 3, formula feeding only. Milk NO concentration was measured as the sum of nitrite and nitrate using the Griess reaction. RESULTS: The highest mean milk NO concentration was on day 4 in all groups, but the peak value in group 3 was significantly lower (P<0.0001) than in other groups. The milk NO concentrations of group 1 were significantly greater than those of groups 2 and 3. CONCLUSIONS: We conclude that breast-feeding increases the concentration of NO in milk.
Authors: Juliana O Fernandes; Sandra O C Tella; Ivan S Ferraz; Luiz A D Ciampo; Jose E Tanus-Santos Journal: Mol Cell Biochem Date: 2020-11-25 Impact factor: 3.396
Authors: Gang Ren; Xunzhen Zheng; Matthew Bommarito; Samantha Metzger; Yashna Walia; Joshua Letson; Allen Schroering; Andrea Kalinoski; David Weaver; Christopher Figy; Kam Yeung; Saori Furuta Journal: Sci Rep Date: 2019-04-30 Impact factor: 4.379