Literature DB >> 11852787

[Genome analysis of hepatitis C virus strain 274933RU isolated in Russian Federation].

V V Mokhonov, D V Novikov, E I Samokhvalov, A G Shatalov, N A Selivanov, A G Prilipov, D K L'vov.   

Abstract

Five overlapping cDNA fragments of hepatitis C virus (HCV) isolate 274933RU, obtained by RT-PCR, were amplified and cloned. Complete nucleotide RNA sequence has been determined. The genomic organization of 274933RU was, from 5' to 3' terminals, 5' UTR (341 nt), polyprotein ORF (9033 nt), 3' UTR (40 nt except for the poly(U-UC) and polypyrimidine stretch), and X-tail (98 nt). Phylogenetic analysis of the core and NS5 genes showed that the isolated strain belonged to HCV 1b subtype.

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Year:  2002        PMID： 11852787

Source DB:  PubMed          Journal:  Vopr Virusol        ISSN： 0507-4088


  4 in total

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3.  Enhancement of the expression of HCV core gene does not enhance core-specific immune response in DNA immunization: advantages of the heterologous DNA prime, protein boost immunization regimen.

Authors:  Ekaterina Alekseeva; Irina Sominskaya; Dace Skrastina; Irina Egorova; Elizaveta Starodubova; Eriks Kushners; Marija Mihailova; Natalia Petrakova; Ruta Bruvere; Tatyana Kozlovskaya; Maria Isaguliants; Paul Pumpens
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Authors:  Irina Sominskaya; Juris Jansons; Anastasija Dovbenko; Natalia Petrakova; Ilva Lieknina; Marija Mihailova; Oleg Latyshev; Olesja Eliseeva; Irina Stahovska; Inara Akopjana; Ivars Petrovskis; Maria Isaguliants
Journal:  J Immunol Res       Date:  2015-11-02       Impact factor: 4.818
  4 in total

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