Literature DB >> 1185164

Monoaminergic neurotoxins: are they selective?

F E Bloom.   

Abstract

Introduction of 6-hydroxydopamine into the cerebrospinal fluid produces a selective destruction of adrenergic pathways. However, the selectivity of interstitial injections of 6-hydroxydopamine for catecholamine elements is critically dependent upon the dose and volume of injection must be evaluated by biochemical and cytochemical indices.

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Year:  1975        PMID： 1185164     DOI： 10.1007/bf01670127

Source DB:  PubMed          Journal:  J Neural Transm            Impact factor:   3.575


  7 in total

Review 1.  Mechanisms of action of 6-hydroxydopamine.

Authors:  C Sachs; G Jonsson
Journal:  Biochem Pharmacol       Date:  1975-01-01       Impact factor: 5.858

2.  Injection of 6-hydroxydopamine and hydrogen peroxide into the substantia nigra and lateral ventricle of the cat: specific and nonspecific effects on striatal biogenic amines.

Authors:  S M Stahl; A C Daniels; D Derda; R Spehlmann
Journal:  J Neurochem       Date:  1975-01       Impact factor: 5.372

Review 3.  Selective lesions of central catecholamine pathways: application in functional studies.

Authors:  U Ungerstedt
Journal:  Neurosci Res (N Y)       Date:  1973

4.  An electron microscopic study of selective, acute degeneration of sympathetic nerve terminals after administration of 6-hydroxydopamine.

Authors:  J P Tranzer; H Thoenen
Journal:  Experientia       Date:  1968-02-15

5.  [Effects of the intraventricular injection of 6-hydroxydopamine. I. On the cerebral monoamines of the cat].

Authors:  F Petitjean; R Laguzzi; F Sordet; M Jouvet; J F Pujol
Journal:  Brain Res       Date:  1972-12-24       Impact factor: 3.252

6.  6-Hydroxy-dopamine induced degeneration of central monoamine neurons.

Authors:  U Ungerstedt
Journal:  Eur J Pharmacol       Date:  1968-12       Impact factor: 4.432

7.  Cytochemical and physiological effects of 6-hydroxydopamine on periarteriolar nerves of frogs.

Authors:  G R Siggins; F E Bloom
Journal:  Circ Res       Date:  1970-07       Impact factor: 17.367
  7 in total

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