Literature DB >> 11850925

Myotonia and keratoderma induced by 20,25 diazacholestenol.

P C Anderson1, J M Martt.   

Abstract

A new inhibitor of cholesterol synthesis, 20,25 diazachlestenol, produced myotonia in 31 persons; and, in six of these, a keratoderma which resembles the natural disease, keratoderma climactericum. These observations further emphasize the importance of normal lipid synthesis in orderly cornification.

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Year:  1965        PMID: 11850925

Source DB:  PubMed          Journal:  Arch Dermatol        ISSN: 0003-987X


  3 in total

1.  [Experimental myotonia induced by amines. Changes in the fatty acid pattern of phosphatides in rat muscles].

Authors:  D Seiler; E Kuhn
Journal:  Klin Wochenschr       Date:  1969-10-15

Review 2.  Lipids and the epidermal permeability barrier.

Authors:  P M Elias
Journal:  Arch Dermatol Res       Date:  1981       Impact factor: 3.017

3.  Stratum corneum lipids in disorders of cornification: increased cholesterol sulfate content of stratum corneum in recessive x-linked ichthyosis.

Authors:  M L Williams; P M Elias
Journal:  J Clin Invest       Date:  1981-12       Impact factor: 14.808

  3 in total

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