Literature DB >> 11849958

Protein transduction technology.

Jehangir S Wadia1, Steven F Dowdy.   

Abstract

Intracellular delivery of macromolecules remains problematic because of the bioavailability restriction imposed by the cell membrane. Recent studies on protein transduction domains have circumvented this barrier, however, and have resulted in the delivery of peptides, full-length proteins, iron beads, liposomes, and radioactive isotopes into cells in culture and animal models in vivo.

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Year:  2002        PMID: 11849958     DOI: 10.1016/s0958-1669(02)00284-7

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN: 0958-1669            Impact factor:   9.740


  121 in total

1.  TAT fusion protein transduction into isolated mitochondria is accelerated by sodium channel inhibitors.

Authors:  Jayanagendra P Rayapureddi; Wendy J Tomamichel; Sonia T Walton; R Mark Payne
Journal:  Biochemistry       Date:  2010-11-09       Impact factor: 3.162

Review 2.  Generation of pluripotent stem cells without the use of genetic material.

Authors:  Akon Higuchi; Qing-Dong Ling; S Suresh Kumar; Murugan A Munusamy; Abdullah A Alarfaj; Yung Chang; Shih-Hsuan Kao; Ke-Chen Lin; Han-Chow Wang; Akihiro Umezawa
Journal:  Lab Invest       Date:  2014-11-03       Impact factor: 5.662

3.  Insight into the mechanism of the peptide-based gene delivery system MPG: implications for delivery of siRNA into mammalian cells.

Authors:  Federica Simeoni; May C Morris; Frederic Heitz; Gilles Divita
Journal:  Nucleic Acids Res       Date:  2003-06-01       Impact factor: 16.971

4.  Peptide-linked molecular beacons for efficient delivery and rapid mRNA detection in living cells.

Authors:  Nitin Nitin; Philip J Santangelo; Gloria Kim; Shuming Nie; Gang Bao
Journal:  Nucleic Acids Res       Date:  2004-04-14       Impact factor: 16.971

5.  On the mechanisms of the internalization of S4(13)-PV cell-penetrating peptide.

Authors:  Miguel Mano; Cristina Teodósio; Artur Paiva; Sérgio Simões; Maria C Pedroso de Lima
Journal:  Biochem J       Date:  2005-09-01       Impact factor: 3.857

6.  Real-time transmembrane translocation of penetratin driven by light-generated proton pumping.

Authors:  Jörgen Björklund; Henrik Biverståhl; Astrid Gräslund; Lena Mäler; Peter Brzezinski
Journal:  Biophys J       Date:  2006-06-16       Impact factor: 4.033

7.  Specific patterns of Cdc42 activity are related to distinct elements of T cell polarization.

Authors:  Irina Tskvitaria-Fuller; Abhinav Seth; Neeta Mistry; Hua Gu; Michael K Rosen; Christoph Wülfing
Journal:  J Immunol       Date:  2006-08-01       Impact factor: 5.422

Review 8.  Oral delivery of human biopharmaceuticals, autoantigens and vaccine antigens bioencapsulated in plant cells.

Authors:  Kwang-Chul Kwon; Dheeraj Verma; Nameirakpam D Singh; Roland Herzog; Henry Daniell
Journal:  Adv Drug Deliv Rev       Date:  2012-10-23       Impact factor: 15.470

Review 9.  Cell penetrating peptide inhibitors of nuclear factor-kappa B.

Authors:  J S Orange; M J May
Journal:  Cell Mol Life Sci       Date:  2008-11       Impact factor: 9.261

10.  Fluorescent sterols monitor cell penetrating peptide Pep-1 mediated uptake and intracellular targeting of cargo protein in living cells.

Authors:  Anca D Petrescu; Aude Vespa; Huan Huang; Avery L McIntosh; Friedhelm Schroeder; Ann B Kier
Journal:  Biochim Biophys Acta       Date:  2008-10-17
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