Literature DB >> 11849834

Hepatoprotective activity of two plants belonging to the Apiaceae and the Euphorbiaceae family.

Bahar Ahmed1, Tanveer Alam, Manoj Varshney, Shah Alam Khan.   

Abstract

The different extracts of Apium graveolens Linn. (Apiaceae) and Croton oblongifolius Roxb. (Euphorbiaceae) were tested for their hepatoprotective activity against CCl(4) induced hepatotoxicity in albino rats. The degree of protection was measured by using biochemical parameters like serum transaminases (SGOT and SGPT), alkaline phosphatase, total protein and albumin. The methanolic extracts showed the most significant hepatoprotective activity comparable with standard drug silymarin. Other extracts namely petroleum ether and acetone also exhibited a potent activity.

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Year:  2002        PMID： 11849834     DOI： 10.1016/s0378-8741(01)00392-0

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


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