| Literature DB >> 11849748 |
Takahiro Uenishi1, Shoji Kubo, Kazuhiro Hirohashi, Takatsugu Yamamoto, Masao Ogawa, Hiromu Tanaka, Taichi Shuto, Hiroaki Kinoshita.
Abstract
The clinicopathologic findings in patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC) positive for biliary markers, those related to the hepatic progenitor cells, were investigated. Cytokeratin (CK) 19 was reactive for HCCs only in patients with prior hepatitis B virus (HBV) infection. The proportions of patients with prior HBV infection and poorly differentiated HCC were significantly higher among those with CK 19-positive HCC than among those with CK 19-negative HCC. Some HCCs develop from the hepatic progenitor cells in patients with HCV infection and prior HBV infection, which may affect the clinicopathologic findings of HCV-related HCCs.Entities:
Mesh：
Substances：
Year: 2002 PMID： 11849748 DOI： 10.1016/s0304-3835(01)00813-8
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679