BACKGROUND: Microdermabrasion has become a popular method of skin rejuvenation for treating dyschromia, fine wrinkles, and mild scarring. OBJECTIVE: To analyze the onset and extent of the dermatologic changes associated with microdermabrasion. METHODS: Ten volunteers, ages 31-62 years, underwent a series of six aluminum oxide microdermabrasion facial treatments 7-10 days apart. Skin biopsy specimens were obtained prior to the study, after three treatments, and after six treatments. RESULTS: Compared to the controls, the treated areas demonstrated the following histologic changes: thickening of the epidermis and dermis, flattening of the rete pegs, vascular ectasia and perivascular inflammation, and hyalinization of the papillary dermis with newly deposited collagen and elastic fibers. CONCLUSION: This study suggests that microdermabrasion produces clinical improvement by a mechanism resembling a reparative process at the dermal and epidermal levels.
BACKGROUND: Microdermabrasion has become a popular method of skin rejuvenation for treating dyschromia, fine wrinkles, and mild scarring. OBJECTIVE: To analyze the onset and extent of the dermatologic changes associated with microdermabrasion. METHODS: Ten volunteers, ages 31-62 years, underwent a series of six aluminum oxide microdermabrasion facial treatments 7-10 days apart. Skin biopsy specimens were obtained prior to the study, after three treatments, and after six treatments. RESULTS: Compared to the controls, the treated areas demonstrated the following histologic changes: thickening of the epidermis and dermis, flattening of the rete pegs, vascular ectasia and perivascular inflammation, and hyalinization of the papillary dermis with newly deposited collagen and elastic fibers. CONCLUSION: This study suggests that microdermabrasion produces clinical improvement by a mechanism resembling a reparative process at the dermal and epidermal levels.
Authors: Gabriella Fabbrocini; M C Annunziata; V D'Arco; V De Vita; G Lodi; M C Mauriello; F Pastore; G Monfrecola Journal: Dermatol Res Pract Date: 2010-10-14
Authors: Abdul Ahad; Mohammad Raish; Yousef A Bin Jardan; Abdullah M Al-Mohizea; Fahad I Al-Jenoobi Journal: Pharmaceutics Date: 2021-01-14 Impact factor: 6.321