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Literature DB >> 11848920

Inorganic Mimics of Ribonucleases and Ribozymes: From Random Cleavage to Sequence-Specific Chemistry to Catalytic Antisense Drugs.

Bobby N. Trawick¹, Andrew T. Daniher, James K. Bashkin.

Abstract

Year: 1998 PMID： 11848920 DOI： 10.1021/cr960422k

Source DB: PubMed Journal: Chem Rev ISSN： 0009-2665 Impact factor: 60.622

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20 in total

1. The reactivity of phosphodiester bonds within linear single-stranded oligoribonucleotides is strongly dependent on the base sequence.

Authors: Ulla Kaukinen; Sari Lyytikäinen; Satu Mikkola; Harri Lönnberg
Journal: Nucleic Acids Res Date: 2002-01-15 Impact factor: 16.971

2. Artificial ribonucleases: oligonucleotide-peptide conjugates that cleave RNA at the GpX and PypA phosphodiester bonds.

Authors: N L Mironova; D V Pyshnyi; E M Ivanova; M A Zenkova; G J Gross; V V Vlasov
Journal: Dokl Biochem Biophys Date: 2002 Jul-Aug Impact factor: 0.788

3. Efficient new ribozyme mimics: direct mapping of molecular design principles from small molecules to macromolecular, biomimetic catalysts.

Authors: W C Putnam; A T Daniher; B N Trawick; J K Bashkin
Journal: Nucleic Acids Res Date: 2001-05-15 Impact factor: 16.971

Review 4. Ribozyme speed limits.

Authors: Gail Mitchell Emilsson; Shingo Nakamura; Adam Roth; Ronald R Breaker
Journal: RNA Date: 2003-08 Impact factor: 4.942

5. Sequence-specific artificial ribonucleases. I. Bis-imidazole-containing oligonucleotide conjugates prepared using precursor-based strategy.

Authors: Natalia G Beloglazova; Martin M Fabani; Marina A Zenkova; Elena V Bichenkova; Nikolai N Polushin; Vladimir V Sil'nikov; Kenneth T Douglas; Valentin V Vlassov
Journal: Nucleic Acids Res Date: 2004-07-23 Impact factor: 16.971

6. Covalently attached oligodeoxyribonucleotides induce RNase activity of a short peptide and modulate its base specificity.

Authors: Nadezhda L Mironova; Dmytryi V Pyshnyi; Eugenya M Ivanova; Marina A Zenkova; Hans J Gross; Valentin V Vlassov
Journal: Nucleic Acids Res Date: 2004-03-26 Impact factor: 16.971

Inorganic Mimics of Ribonucleases and Ribozymes: From Random Cleavage to Sequence-Specific Chemistry to Catalytic Antisense Drugs.

1. The reactivity of phosphodiester bonds within linear single-stranded oligoribonucleotides is strongly dependent on the base sequence.

2. Artificial ribonucleases: oligonucleotide-peptide conjugates that cleave RNA at the GpX and PypA phosphodiester bonds.

3. Efficient new ribozyme mimics: direct mapping of molecular design principles from small molecules to macromolecular, biomimetic catalysts.

Review 4. Ribozyme speed limits.

5. Sequence-specific artificial ribonucleases. I. Bis-imidazole-containing oligonucleotide conjugates prepared using precursor-based strategy.

6. Covalently attached oligodeoxyribonucleotides induce RNase activity of a short peptide and modulate its base specificity.

7. Cooperation of metal-ion fixation and target-site activation for efficient site-selective RNA scission.

8. Recruitment of divalent metal ions by incorporation of 4-thio-2'-deoxythymidine or 4-thio-2'-deoxyuridine into DNA.

9. Oligoamine-acridine conjugates for promotion of gap-selective DNA hydrolysis by Ce(IV)/EDTA complex.

10. Preferential hydrolysis of gap and bulge sites in DNA by Ce(IV)/EDTA complex.