Literature DB >> 11848546

Delirium after interleukin-2 and alpha-interferon therapy for renal cell carcinoma.

J H van Steijn1, P Nieboer, G A Hospers, E G de Vries, N H Mulder.   

Abstract

A 55-year-old man receiving alpha-interferon and interleukin-2 therapy for renal cell carcinoma presented with seizures and delirium. A CT-scan of the cerebrum did not reveal any disorder. Both alpha-interferon and interleukin-2 were stopped. Treatment with steroids led to complete regression of central nervous system symptomatology. We emphasize the importance of ruling out iatrogenesis in patients treated with alpha-interferon and/or interleukin-2 who display neuropsychiatric symptoms.

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Year:  2001        PMID： 11848546

Source DB:  PubMed          Journal:  Anticancer Res        ISSN： 0250-7005            Impact factor:   2.480


  3 in total

1.  Role of CRP, TNF-a, and IGF-1 in Delirium Pathophysiology.

Authors:  Mehmet Alper Çinar; Adem Balikçi; Erdim Sertoğlu; A K Mehmet; Muhittin A Serdar; Kamil Nahit Özmenler
Journal:  Noro Psikiyatr Ars       Date:  2014-12-01       Impact factor: 1.339

2.  Systemic inflammation induces acute working memory deficits in the primed brain: relevance for delirium.

Authors:  Carol Murray; David J Sanderson; Chris Barkus; Robert M J Deacon; J Nicholas P Rawlins; David M Bannerman; Colm Cunningham
Journal:  Neurobiol Aging       Date:  2010-05-14       Impact factor: 4.673

Review 3.  At the extreme end of the psychoneuroimmunological spectrum: delirium as a maladaptive sickness behaviour response.

Authors:  Colm Cunningham; Alasdair M J Maclullich
Journal:  Brain Behav Immun       Date:  2012-08-03       Impact factor: 7.217
  3 in total

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