| Literature DB >> 11848228 |
Kunihiro Sumoto1, Nobuko Mibu, Kazumi Yokomizo, Masaru Uyeda.
Abstract
New diphenylmethane-type 2,2'-dihydroxybisphenols (5a-d) were prepared regioselectively in good yields. We evaluated the antiviral activity of some bisphenol derivatives synthesized by the plaque reduction assay. Most of the compounds showed significant antiviral activity and the 4,4'-dihydroxybisphenol derivative (10) showed higher activity than 2,2'-bisphenol derivatives. This compound had EC50 value of 1.8 microg/ml.Entities:
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Year: 2002 PMID： 11848228 DOI： 10.1248/cpb.50.298
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645