| Literature DB >> 1184730 |
J Fishman, R M Boyar, L Hellman.
Abstract
The metabolism of estradiol in girls with anorexia nervosa was compared with obese subjects and normal weight, age and sex matched controls. Increasing body weight was accompanied by a sharp decrease in 2-hydroxylation of estradiol and an increase in 16alpha-hydroxylation. These metabolic changes are discussed in terms of the biological activity of 2-hydroxyestrone and estriol.Entities:
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Year: 1975 PMID: 1184730 DOI: 10.1210/jcem-41-5-989
Source DB: PubMed Journal: J Clin Endocrinol Metab ISSN: 0021-972X Impact factor: 5.958