Literature DB >> 11846690

Synthesis of a sialic acid dimer derivative, 2'alpha-O-benzyl Neu5Ac-alph-(2-->5)Neu5Gc.

Chien-Tai Ren1, Chien-Sheng Chen, Shih-Hsiung Wu.   

Abstract

The preparation of a disaccharide 2, Neu5Ac-alpha-(2-->5)Neu5Gc having a alpha-benzyl protecting group at the reducing end, by the coupling of the easily accessible building units 4 and 5 is described. Subsequent deprotection of the coupling adduct led to the isolation of the target compound 2 in high yield.

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Year:  2002        PMID: 11846690     DOI: 10.1021/jo015930v

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  3 in total

Review 1.  Advances in the biology and chemistry of sialic acids.

Authors:  Xi Chen; Ajit Varki
Journal:  ACS Chem Biol       Date:  2010-02-19       Impact factor: 5.100

2.  Structure-Activity Relationship Study of the Neuritogenic Potential of the Glycan of Starfish Ganglioside LLG-3 (‡).

Authors:  Megumi Yamagishi; Ritsuko Hosoda-Yabe; Hideki Tamai; Miku Konishi; Akihiro Imamura; Hideharu Ishida; Tomio Yabe; Hiromune Ando; Makoto Kiso
Journal:  Mar Drugs       Date:  2015-12-05       Impact factor: 5.118

Review 3.  Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides.

Authors:  Anoopjit Singh Kooner; Hai Yu; Xi Chen
Journal:  Front Immunol       Date:  2019-08-28       Impact factor: 7.561

  3 in total

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