Literature DB >> 11846245

Liver enzymes as predictors of liver damage due to blunt abdominal trauma in children.

Subhash R Puranik1, Janice S Hayes, Julie Long, Maria Mata.   

Abstract

BACKGROUND: Blunt abdominal trauma in children can result in injury to the liver. In hemodynamically stable patients, initial evaluation of liver transaminase levels may be useful in determining the need for computed tomography (CT).
METHODS: We reviewed the medical records of 44 hemodynamically stable children who had abdominal CT and who also had liver enzyme determinations as the initial workup.
RESULTS: Liver enzymes were found to be elevated in all but one patient with CT confirmed hepatic injury. The sensitivity and specificity of elevated liver enzyme levels were 92.9% and 100%, respectively, for predicting liver injury.
CONCLUSION: When hemodynamically stable pediatric patients with blunt abdominal trauma have AST levels >400 and/or ALT levels >250 IU/L, abdominal CT is indicated. Children in this study with serum transaminase levels below these values were at decreased risk of liver injury.

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Mesh:

Year:  2002        PMID: 11846245

Source DB:  PubMed          Journal:  South Med J        ISSN: 0038-4348            Impact factor:   0.954


  8 in total

1.  Analysis of urobilinogen and urine bilirubin for intra-abdominal injury in blunt trauma patients.

Authors:  Julie Gorchynski; Kevin Dean; Craig L Anderson
Journal:  West J Emerg Med       Date:  2009-05

2.  Screening for occult abdominal trauma in children with suspected physical abuse.

Authors:  Wendy Gwirtzman Lane; Howard Dubowitz; Patricia Langenberg
Journal:  Pediatrics       Date:  2009-11-23       Impact factor: 7.124

3.  A Reliable Screening Test to Predict Liver Injury in Pediatric Blunt Torso Trauma.

Authors:  Feng-Yuan Chu; Hung-Jung Lin; How-Ran Guo; Tsan-Hsing Liu; Ning-Ping Foo; Kuo-Tai Chen
Journal:  Eur J Trauma Emerg Surg       Date:  2009-09-05       Impact factor: 3.693

4.  Risk factors for liver abscess formation in patients with blunt hepatic injury after non-operative management.

Authors:  C-P Hsu; S-Y Wang; Y-P Hsu; H-W Chen; B-C Lin; S-C Kang; K-C Yuan; E-H Liu; I-M Kuo; C-H Liao; C-H Ouyang; S-J Yang
Journal:  Eur J Trauma Emerg Surg       Date:  2013-10-24       Impact factor: 3.693

5.  Role of elevated liver transaminase levels in the diagnosis of liver injury after blunt abdominal trauma.

Authors:  Zhiqiang Tian; Hong Liu; Xiaofang Su; Zheng Fang; Zhitao Dong; Changchun Yu; Kunlun Luo
Journal:  Exp Ther Med       Date:  2012-05-15       Impact factor: 2.447

6.  The blood parameters and liver function changed inconsistently among children between burns and traumatic injuries.

Authors:  Chan Nie; Tao Wang; Huiting Yu; Xue Wang; Xueqin Zeng; Zairong Wei; Xiuquan Shi
Journal:  PeerJ       Date:  2019-02-11       Impact factor: 2.984

7.  Posttraumatic levels of liver enzymes can reduce the need for CT in children: a retrospective cohort study.

Authors:  Peter James Bruhn; Lene Østerballe; Jens Hillingsø; Lars Bo Svendsen; Frederik Helgstrand
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2016-08-25       Impact factor: 2.953

8.  Defining the optimal cut-off values for liver enzymes in diagnosing blunt liver injury.

Authors:  Tomohide Koyama; Hirohisa Hamada; Masamichi Nishida; Paal A Naess; Christine Gaarder; Tetsuya Sakamoto
Journal:  BMC Res Notes       Date:  2016-01-25
  8 in total

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