Literature DB >> 1184478

A new antibiotic, fumaramidmycin. II. Isolation, structure and syntheses.

Y Suhara, H B Maruyama, Y Koto, Y Miyasaka, K Yokose.   

Abstract

A new antibiotic fumaramidmycin produced by Streptomyces kurssanovii NR-7GG1 was isolated as colorless crystals. The structure was shown to be N-(phenylacetyl) fumaramide. Starting from fumaramic acid, fumaramidmycin has been synthesized in good yield, in which the key stage involves N-acylated imino ether formation followed by mild acid hydrolysis. Five analogues of fumaramidmycin have also been prepared.

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Year:  1975        PMID: 1184478     DOI: 10.7164/antibiotics.28.648

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  2 in total

1.  Syntheses and biological activity of some derivatives of C-9154 antibiotic.

Authors:  Isaac Asusheyi Bello; George Iloegbulam Ndukwe; Joseph Olorunju Amupitan; Rachael Gbekele Ayo; Francis Oluwole Shode
Journal:  Int J Med Chem       Date:  2012-08-06

2.  Syntheses and in vitro biological activity of some derivatives of C-9154 antibiotic.

Authors:  Isaac Asusheyi Bello; George Iloegbulam Ndukwe; Joseph Olorunju Amupitan; Rachael Gbekele Ayo; Francis Oluwole Shode
Journal:  Int J Med Chem       Date:  2012-11-25
  2 in total

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