Literature DB >> 11844708

Meiosis activating sterols derived from diosgenin.

Anthony Murray1, Christian Grøndahl, Jan L Ottesen, Peter Faarup.   

Abstract

Continuing research based on the meiosis activation properties of the endogenous sterol FF-MAS is reported. The synthesis and SAR of 16- and 26-substituted sterols are described, utilising diosgenin as starting material. Selected sterols were tested for their ability to induce oocyte maturation in hypoxanthine arrested mouse oocytes in vitro.

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Year:  2002        PMID: 11844708     DOI: 10.1016/s0960-894x(01)00840-x

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  Total syntheses of (-)-alpha-kainic acid and (+)-alpha-allokainic acid via stereoselective C-H insertion and efficient 3,4-stereocontrol.

Authors:  Young Chun Jung; Cheol Hwan Yoon; Edward Turos; Kyung Soo Yoo; Kyung Woon Jung
Journal:  J Org Chem       Date:  2007-11-29       Impact factor: 4.354

  1 in total

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