Literature DB >> 11843915

In vitro susceptibility of Mycobacterium tuberculosis to fusidic acid.

C Cicek-Saydam1, C Cavusoglu, D Burhanoglu, S Hilmioglu, N Ozkalay, A Bilgic.   

Abstract

The aim of this study was to determine the in vitro susceptibility of 170 clinical isolates of Mycobacterium tuberculosis to fusidic acid using a proportion dilution method. Nineteen isolates were resistant to at least one first-line anti-tuberculosis drug. A total of 1.8% of the isolates were resistant to fusidic acid. Fusidic acid should be evaluated clinically as a potential supplementary drug for the treatment of infections due to multidrug-resistant strains of M. tuberculosis.

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Year:  2001        PMID: 11843915     DOI: 10.1046/j.1469-0691.2001.00341.x

Source DB:  PubMed          Journal:  Clin Microbiol Infect        ISSN: 1198-743X            Impact factor:   8.067


  2 in total

1.  Novel antimycobacterial C-21 amide derivatives of the antibiotic fusidic acid: synthesis, pharmacological evaluation and rationalization of media-dependent activity using molecular docking studies in the binding site of human serum albumin.

Authors:  Godwin Akpeko Dziwornu; Stephanie Kamunya; Tando Ntsabo; Kelly Chibale
Journal:  Medchemcomm       Date:  2019-04-18       Impact factor: 3.597

2.  Innovation Experiences from Africa-Led Drug Discovery at the Holistic Drug Discovery and Development (H3D) Centre.

Authors:  Vinayak Singh; Dickson Mambwe; Constance Mawunyo Korkor; Kelly Chibale
Journal:  ACS Med Chem Lett       Date:  2022-07-11       Impact factor: 4.632

  2 in total

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