| Literature DB >> 11842334 |
A Suksamrarn1, S Kumpun, K Kirtikara, B Yingyongnarongkul, S Suksamrarn.
Abstract
A new iridoid, pedunculariside, together with the known iridoid agnuside were isolated from the butanol extract of Vitex peduncularis stem bark. Both pedunculariside and agnuside showed preferential inhibition of COX-2, with IC50 values of 0.15 +/- 0.21 mg/ml and 0.026 +/- 0.015 mg/ml respectively, while having only small inhibitory effects on COX-1. Both compounds did not exhibit cytotoxicity against vero cells.Entities:
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Year: 2002 PMID： 11842334 DOI： 10.1055/s-2002-20048
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352