Literature DB >> 11841349

Vascular-platelet and plasma hemostasis regulators from bloodsucking animals.

A V Basanova1, I P Baskova, L L Zavalova.   

Abstract

Saliva of bloodsuckers (leeches, insects, ticks, vampire bats) contains various regulators of some hemostatic stages. This review summarizes information on their structural characteristics and mechanisms of action. Most bloodsuckers are shown to inhibit vascular-platelet hemostasis by blocking collagen-induced platelet adhesion/aggregation. Plasma hemostasis is inhibited by blocking activation of factor X or factor Xa directly.

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Year:  2002        PMID： 11841349     DOI： 10.1023/a:1013968618120

Source DB:  PubMed          Journal:  Biochemistry (Mosc)        ISSN： 0006-2979            Impact factor:   2.487


  9 in total

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