Literature DB >> 1184118

Prevention of spontaneous autoimmunity to DNA in NZB/Swiss mice by treatment with natural double-stranded RNA.

J Rovenský, J Doskocil, J Pekárek, L Borecký, D Zitnan, J Svejcar.   

Abstract

Data are presented demonstrating the prevention of spontaneous autoimmune disease in NZB/Swiss mice treated natural double-stranded RNA. The successful treatment of animals was followed both by improvement in clinical manifestations and by the migration inhibition test performed with DNA as antigen. The reasons for the successful employment of natural double-stranded RNA are thought to be in its physicochemical properties.

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Year:  1975        PMID： 1184118      PMCID： PMC1446046     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  11 in total

1.  A new method for the isolation of deoxyribonucleic acids; evidence on the nature of bonds between deoxyribonucleic acid and protein.

Authors:  K S KIRBY
Journal:  Biochem J       Date:  1957-07       Impact factor: 3.857

2.  A new method for the isolation of ribonucleic acids from mammalian tissues.

Authors:  K S KIRBY
Journal:  Biochem J       Date:  1956-11       Impact factor: 3.857

3.  Double-stranded f 2 phage RNA as interferon inducer.

Authors:  J Doskocil; N Fuchsberger; J Vetrák; V Lackovic; L Borecký
Journal:  Acta Virol       Date:  1971-11       Impact factor: 1.162

4.  The pathogenesis of autoimmunity in New Zealand mice. II. Acceleration of glomerulonephritis by polyinosinic-polycytidylic acid.

Authors:  D F Carpenter; A D Steinberg; P H Schur; N Talal
Journal:  Lab Invest       Date:  1970-12       Impact factor: 5.662

5.  A nuclease from animal serum which hydrolyzes double-stranded RNA.

Authors:  R Stern
Journal:  Biochem Biophys Res Commun       Date:  1970-11-09       Impact factor: 3.575

6.  The pathogenesis of autoimmunity in New Zealand mice. 3. Factors influencing the formation of anti-nucleic acid antibodies.

Authors:  A D Steinberg; T Pincus; N Talal
Journal:  Immunology       Date:  1971-04       Impact factor: 7.397

7.  Dependence of antiviral activity on molecular weight in an interferon stimulator of the natural double-stranded RNA type.

Authors:  E Gajdosová; J Doskocil; V Mayer
Journal:  Acta Virol       Date:  1973-05       Impact factor: 1.162

8.  Antibodies to ribonucleic acid in systemic lupus erythematosus.

Authors:  P H Schur; M Monroe
Journal:  Proc Natl Acad Sci U S A       Date:  1969-08       Impact factor: 11.205

9.  The pathogenesis of autoimmunity in New Zealand mice, I. Induction of antinucleic acid antibodies by polyinosinic-polycytidylic acid.

Authors:  A D Steinberg; S Baron; N Talal
Journal:  Proc Natl Acad Sci U S A       Date:  1969-08       Impact factor: 11.205

10.  Further implication of murine leukemia-like virs in the disorders of NZB mice.

Authors:  R C Mellors; T Aoki; R J Huebner
Journal:  J Exp Med       Date:  1969-05-01       Impact factor: 14.307
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  1 in total

1.  Interferon treatment of NZB mice: accelerated progression of autoimmune disease.

Authors:  H Heremans; A Billiau; A Colombatti; J Hilgers; P de Somer
Journal:  Infect Immun       Date:  1978-09       Impact factor: 3.441
  1 in total

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