| Literature DB >> 11839609 |
Megumi Fujii1, Keijiro Fukazawa, Chihiro Hatta, Hiroki Yasuno, Masafumi Sakagami.
Abstract
The olfactory acuity of 29 patients receiving laryngectomy was prospectively studied. The olfactory acuity was evaluated by Jet Stream Olfactometer (JSO) and Alinamin test preoperatively and at 3, 6 and 12 months postoperatively. The findings of nasal/olfactory mucosae were also observed by rigid endoscope. Based on the results of JSO, the averages of detection/recognition thresholds tended to increase 3 months postoperatively, then the averaged thresholds tended to decrease thereafter. There were significant differences between preoperative values and those 3 months after surgery, but there were no significant differences between preoperative values and these 6/12 months after surgery. Nasal respiratory mucosae observed 12 months after laryngectomy showed atrophic nasal mucosa in 11/14 patients. However, olfactory mucosae appeared normal in all of the patients observed. These results suggested that the function of the olfactory epithelium remained intact after laryngectomy.Entities:
Mesh:
Year: 2002 PMID: 11839609 DOI: 10.1093/chemse/27.2.117
Source DB: PubMed Journal: Chem Senses ISSN: 0379-864X Impact factor: 3.160