| Literature DB >> 11839292 |
Thomas Caspari1, Antony M Carr.
Abstract
How checkpoint pathways recognise double-strand breaks has long been a mystery. Recent studies have found that two distinct checkpoint protein complexes associate independently with chromatin at the sites of DNA damage. Why do two distinct mechanisms recognise strand lesions, and what does this tell us about the checkpoint pathways?Mesh：
Substances：
Year: 2002 PMID： 11839292 DOI： 10.1016/s0960-9822(02)00673-5
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834