Literature DB >> 11838901

Crossreactivity of SLE autoantibodies with 70 kDa heat shock proteins of Mycobacterium tuberculosis.

S Tasneem1, N Islam, R Ali.   

Abstract

Heat shock proteins (hsp) may be involved in the initiation and perpetuation of autoimmune diseases. In order to investigate the possible role of hsp and other intracellular proteins of Mycobacterium tuberculosis in the autoantibody production in SLE, the immuno-crossreactivity of SLE autoantibodies with Mycobacterium tuberculosis sonic extract and hsp-70 kDa was investigated. These proteins showed significant binding with Protein A-Sepharose isolated SLE IgG. Western blotting of hsp-70 with SLE IgG showed strong recognition, suggesting possible involvement of hsp and other intracellular proteins of Mycobacterium tuberculosis in the autoantibody induction in SLE.

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11838901     DOI： 10.1111/j.1348-0421.2001.tb01323.x

Source DB:  PubMed          Journal:  Microbiol Immunol        ISSN： 0385-5600            Impact factor:   1.955


  7 in total

Review 1.  Mycobacterium tuberculosis, autoimmunity, and vitamin D.

Authors:  Yinon Shapira; Nancy Agmon-Levin; Yehuda Shoenfeld
Journal:  Clin Rev Allergy Immunol       Date:  2010-04       Impact factor: 8.667

2.  Normal delivery induced stress alters glutathione peroxidase and TNF-α in elderly primigravidas mononuclear cells.

Authors:  Nasreen Noor; Najmul Islam; Shagufta Moin; Abbas Ali Mahdi; Sapna Jaiswal; Farzana Bano
Journal:  Indian J Clin Biochem       Date:  2008-10-01

3.  Suppression of mycobacterium tuberculosis induced reactive oxygen species and tumor necrosis factor-alpha activity in human monocytes of systemic lupus erythematosus patients by reduced glutathione.

Authors:  Shah Farhan Azfar; Najmul Islam
Journal:  Oman Med J       Date:  2012-01

4.  Amniotic fluid heat shock protein 70 concentration in histologic chorioamnionitis, term and preterm parturition.

Authors:  Tinnakorn Chaiworapongsa; Offer Erez; Juan Pedro Kusanovic; Edi Vaisbuch; Shali Mazaki-Tovi; Francesca Gotsch; Nandor Gabor Than; Pooja Mittal; Yeon Mee Kim; Natalia Camacho; Samuel Edwin; Ricardo Gomez; Sonia S Hassan; Roberto Romero
Journal:  J Matern Fetal Neonatal Med       Date:  2008-07

Review 5.  SLE and infections.

Authors:  Gisele Zandman-Goddard; Yehuda Shoenfeld
Journal:  Clin Rev Allergy Immunol       Date:  2003-08       Impact factor: 8.667

6.  Cd40 but not CD154 knockout mice have reduced inflammatory response in polymicrobial sepsis: a potential role for Escherichia coli heat shock protein 70 in CD40-mediated inflammation in vivo.

Authors:  Anna Nolan; Michael D Weiden; Yoshihiko Hoshino; Jeffrey A Gold
Journal:  Shock       Date:  2004-12       Impact factor: 3.454

7.  Role of hsp90 in systemic lupus erythematosus and its clinical relevance.

Authors:  Hem D Shukla; Paula M Pitha
Journal:  Autoimmune Dis       Date:  2012-10-04
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.