| Literature DB >> 11836501 |
Narumi Ogonuki1, Kimiko Inoue, Yoshie Yamamoto, Yoko Noguchi, Kentaro Tanemura, Osamu Suzuki, Hiroyuki Nakayama, Kunio Doi, Yukiko Ohtomo, Michiko Satoh, Akira Nishida, Atsuo Ogura.
Abstract
Here we report that the lifespan of mice cloned from somatic cells is significantly shorter than that of genotype- and sex-matched controls, most likely due to severe pneumonia and hepatic failure. This finding demonstrates the possibility of long-term deleterious effects of somatic-cell cloning, even after normal birth.Entities:
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Year: 2002 PMID： 11836501 DOI： 10.1038/ng841
Source DB: PubMed Journal: Nat Genet ISSN： 1061-4036 Impact factor: 38.330