Literature DB >> 11836436

B7 costimulation plays an important role in protection from herpes simplex virus type 2-mediated pathology.

Lydia G Thebeau1, Lynda A Morrison.   

Abstract

We have used mice lacking both B7-1 and B7-2 costimulation molecules (B7KO) to investigate the effects of B7 costimulation on herpes simplex virus type 2 (HSV-2) pathogenesis. B7KO mice infected intravaginally with virulent HSV-2 showed more severe genital and neurologic disease and higher mortality rates than their wild-type counterparts. These results suggest that B7 costimulation molecules play an important role in the development of primary immune responses protective against HSV-2.

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Year:  2002        PMID： 11836436      PMCID： PMC153796          DOI： 10.1128/jvi.76.5.2563-2566.2002

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  24 in total

1.  CTLA-4 and CD28 mRNA are coexpressed in most T cells after activation. Expression of CTLA-4 and CD28 mRNA does not correlate with the pattern of lymphokine production.

Authors:  G J Freeman; D B Lombard; C D Gimmi; S A Brod; K Lee; J C Laning; D A Hafler; M E Dorf; G S Gray; H Reiser
Journal:  J Immunol       Date:  1992-12-15       Impact factor: 5.422

Review 2.  Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance.

Authors:  V A Boussiotis; J G Gribben; G J Freeman; L M Nadler
Journal:  Curr Opin Immunol       Date:  1994-10       Impact factor: 7.486

3.  CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL.

Authors:  L L Lanier; S O'Fallon; C Somoza; J H Phillips; P S Linsley; K Okumura; D Ito; M Azuma
Journal:  J Immunol       Date:  1995-01-01       Impact factor: 5.422

4.  IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression.

Authors:  L Ding; P S Linsley; L Y Huang; R N Germain; E M Shevach
Journal:  J Immunol       Date:  1993-08-01       Impact factor: 5.422

5.  Vaccine-induced serum immunoglobin contributes to protection from herpes simplex virus type 2 genital infection in the presence of immune T cells.

Authors:  L A Morrison; L Zhu; L G Thebeau
Journal:  J Virol       Date:  2001-02       Impact factor: 5.103

6.  Characterization of two conformational forms of the major DNA-binding protein encoded by herpes simplex virus 1.

Authors:  D M Knipe; M P Quinlan; A E Spang
Journal:  J Virol       Date:  1982-11       Impact factor: 5.103

7.  Selective induction of B7/BB-1 on interferon-gamma stimulated monocytes: a potential mechanism for amplification of T cell activation through the CD28 pathway.

Authors:  A S Freedman; G J Freeman; K Rhynhart; L M Nadler
Journal:  Cell Immunol       Date:  1991-10-15       Impact factor: 4.868

8.  Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation.

Authors:  V A Boussiotis; G J Freeman; J G Gribben; J Daley; G Gray; L M Nadler
Journal:  Proc Natl Acad Sci U S A       Date:  1993-12-01       Impact factor: 11.205

9.  Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor.

Authors:  V A Boussiotis; D L Barber; T Nakarai; G J Freeman; J G Gribben; G M Bernstein; A D D'Andrea; J Ritz; L M Nadler
Journal:  Science       Date:  1994-11-11       Impact factor: 47.728

10.  Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function.

Authors:  K S Hathcock; G Laszlo; C Pucillo; P Linsley; R J Hodes
Journal:  J Exp Med       Date:  1994-08-01       Impact factor: 14.307
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  11 in total

1.  Differential requirement for CD28 and CD80/86 pathways of costimulation in the long-term control of murine gammaherpesvirus-68.

Authors:  Ashley B Lyon; Sally R Sarawar
Journal:  Virology       Date:  2006-08-24       Impact factor: 3.616

2.  B cell-specific expression of B7-2 is required for follicular Th cell function in response to vaccinia virus.

Authors:  Samira Salek-Ardakani; Youn Soo Choi; Mohammed Rafii-El-Idrissi Benhnia; Rachel Flynn; Ramon Arens; Stephen Shoenberger; Shane Crotty; Michael Croft; Shahram Salek-Ardakani
Journal:  J Immunol       Date:  2011-03-25       Impact factor: 5.422

3.  CD28 Costimulation Is Required for Development of Herpetic Stromal Keratitis but Does Not Prevent Establishment of Latency.

Authors:  Xiao-Tang Yin; Nicholas K Baugnon; Chloe A Potter; Shannon Tai; Tammie L Keadle; Patrick M Stuart
Journal:  J Virol       Date:  2019-07-30       Impact factor: 5.103

4.  Multiple layers of CD80/86-dependent costimulatory activity regulate primary, memory, and secondary lymphocytic choriomeningitis virus-specific T cell immunity.

Authors:  Jens Eberlein; Bennett Davenport; Tom T Nguyen; Francisco Victorino; Tim Sparwasser; Dirk Homann
Journal:  J Virol       Date:  2011-12-07       Impact factor: 5.103

5.  Virus-encoded b7-2 costimulation molecules enhance the protective capacity of a replication-defective herpes simplex virus type 2 vaccine in immunocompetent mice.

Authors:  Sri P Vagvala; Lydia G Thebeau; Saydra R Wilson; Lynda A Morrison
Journal:  J Virol       Date:  2008-11-05       Impact factor: 5.103

6.  B7 costimulation molecules expressed from the herpes simplex virus 2 genome rescue immune induction in B7-deficient mice.

Authors:  Lydia G Thebeau; Sri P Vagvala; Yee M Wong; Lynda A Morrison
Journal:  J Virol       Date:  2007-09-05       Impact factor: 5.103

7.  Mechanism of reduced T-cell effector functions and class-switched antibody responses to herpes simplex virus type 2 in the absence of B7 costimulation.

Authors:  Lydia G Thebeau; Lynda A Morrison
Journal:  J Virol       Date:  2003-02       Impact factor: 5.103

8.  Replication-defective virus vaccine-induced protection of mice from genital herpes simplex virus 2 requires CD4 T cells.

Authors:  Lynda A Morrison
Journal:  Virology       Date:  2008-04-14       Impact factor: 3.616

9.  CD28/B7-mediated co-stimulation is critical for early control of murine cytomegalovirus infection.

Authors:  Charles H Cook; Li Chen; Jin Wen; Peter Zimmerman; Yingxue Zhang; Joanne Trgovcich; Yang Liu; Jian-Xin Gao
Journal:  Viral Immunol       Date:  2009-04       Impact factor: 2.257

10.  Role of B7 costimulatory molecules in immune responses and T-helper cell differentiation in response to recombinant HagB from Porphyromonas gingivalis.

Authors:  Ping Zhang; Michael Martin; Qiu-Bo Yang; Suzanne M Michalek; Jannet Katz
Journal:  Infect Immun       Date:  2004-02       Impact factor: 3.441
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