Literature DB >> 11836100

Novel steroidal vinyl fluorides as inhibitors of steroid C17(20) lyase.

Joseph P Burkhart1, Philip M Weintraub, Cynthia A Gates, Robert J Resvick, Roy J Vaz, Dirk Friedrich, Michael R Angelastro, Philippe Bey, Norton P Peet.   

Abstract

20-fluoro-17(20)-pregnenolone derivatives were designed as enol mimics of pregnenolone. All of the targeted, novel fluoroolefins were potent inhibitors of C17(20) lyase.

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Year:  2002        PMID： 11836100     DOI： 10.1016/s0968-0896(01)00354-6

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  4 in total

1.  Electrochemical Fluorination of Vinyl Boronates through Donor-Stabilized Vinyl Carbocation Intermediates.

Authors:  Benjamin Wigman; Woojin Lee; Wenjing Wei; Kendall N Houk; Hosea M Nelson
Journal:  Angew Chem Int Ed Engl       Date:  2022-02-03       Impact factor: 15.336

2.  Fluoro-Julia olefination as a mild, high-yielding route to alpha-fluoro acrylonitriles.

Authors:  Maria del Solar; Arun K Ghosh; Barbara Zajc
Journal:  J Org Chem       Date:  2008-10-08       Impact factor: 4.354

3.  Au(I) Catalyzed HF Transfer: Tandem Alkyne Hydrofluorination and Perfluoroarene Functionalization.

Authors:  Daniel Mulryan; Jack Rodwell; Nicholas A Phillips; Mark R Crimmin
Journal:  ACS Catal       Date:  2022-03-01       Impact factor: 13.084

Review 4.  Ethyl dibromofluoroacetate: a versatile reagent for the synthesis of fluorinated molecules.

Authors:  Emilie David; Samuel Couve-Bonnaire; Philippe Jubault; Xavier Pannecoucke
Journal:  Tetrahedron       Date:  2013-10-21       Impact factor: 2.457
  4 in total

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