Literature DB >> 1183607

Cholinergic compounds. V - New synthesis and further pharmacological evaluation of desethermuscarine.

C Melchiorre, F Gualtieri, M Giannella, M Pigini, M L Cingolani, G Gamba, P Pigini, L Rossini.   

Abstract

Two new methods of syntesis of (+/-)-desethermuscarine (I) are reported along with the pharmacological evaluation of (I) extended to several muscarinic and nicotinic receptors.

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Year:  1975        PMID： 1183607     DOI： 10.1002/chin.197532195

Source DB:  PubMed          Journal:  Farmaco Sci        ISSN： 0430-0920


  1 in total

1.  Affinity and efficacy correlate with chemical structure more than potency does in a series of pentatomic cyclic muscarinic agonists.

Authors:  P Angeli; L Brasili; M Giannella; F Gualtieri; M Pigini
Journal:  Br J Pharmacol       Date:  1985-08       Impact factor: 8.739
  1 in total

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