Literature DB >> 11834460

The three modern faces of mercury.

Thomas W Clarkson1.   

Abstract

The three modern "faces" of mercury are our perceptions of risk from the exposure of billions of people to methyl mercury in fish, mercury vapor from amalgam tooth fillings, and ethyl mercury in the form of thimerosal added as an antiseptic to widely used vaccines. In this article I review human exposure to and the toxicology of each of these three species of mercury. Mechanisms of action are discussed where possible. Key gaps in our current knowledge are identified from the points of view both of risk assessment and of mechanisms of action.

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Year:  2002        PMID: 11834460      PMCID: PMC1241144          DOI: 10.1289/ehp.02110s111

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN: 0091-6765            Impact factor:   9.031


  92 in total

1.  Delayed cerebellar disease and death after accidental exposure to dimethylmercury.

Authors:  D W Nierenberg; R E Nordgren; M B Chang; R W Siegler; M B Blayney; F Hochberg; T Y Toribara; E Cernichiari; T Clarkson
Journal:  N Engl J Med       Date:  1998-06-04       Impact factor: 91.245

2.  Brain mercury in neurodegenerative disorders.

Authors:  Y K Fung; A G Meade; E P Rack; A J Blotcky
Journal:  J Toxicol Clin Toxicol       Date:  1997

3.  Methylmercury poisoning in Iraq.

Authors:  F Bakir; S F Damluji; L Amin-Zaki; M Murtadha; A Khalidi; N Y al-Rawi; S Tikriti; H I Dahahir; T W Clarkson; J C Smith; R A Doherty
Journal:  Science       Date:  1973-07-20       Impact factor: 47.728

4.  The assessment of biomarkers to detect nephrotoxicity using an integrated database.

Authors:  S A Taylor; I D Chivers; R G Price; M Arce-Tomas; P Milligan; I Francini; R Alinovi; S Cavazzini; E Bergamaschi; M Vittori; A Mutti; R R Lauwerys; A M Bernard; H A Roels; M E De Broe; G D Nuyts; M M Elseviers; G Hotter; I Ramis; J Rosello; E Gelpi; H Stolte; U Eisenberger; L M Fels
Journal:  Environ Res       Date:  1997-10       Impact factor: 6.498

5.  Neurological abnormalities associated with remote occupational elemental mercury exposure.

Authors:  J W Albers; L R Kallenbach; L J Fine; G D Langolf; R A Wolfe; P D Donofrio; A G Alessi; K A Stolp-Smith; M B Bromberg
Journal:  Ann Neurol       Date:  1988-11       Impact factor: 10.422

6.  Homozygous gene deletions of the glutathione S-transferases M1 and T1 are associated with thimerosal sensitization.

Authors:  G A Westphal; A Schnuch; T G Schulz; K Reich; W Aberer; J Brasch; P Koch; R Wessbecher; C Szliska; A Bauer; E Hallier
Journal:  Int Arch Occup Environ Health       Date:  2000-08       Impact factor: 3.015

7.  Route of decomposition of thiomersal (thimerosal).

Authors:  M Tan; J E Parkin
Journal:  Int J Pharm       Date:  2000-11-04       Impact factor: 5.875

8.  Tissue concentrations of mercury after chronic dosing of squirrel monkeys with thiomersal.

Authors:  B Clark; A J Clarke; P Wood
Journal:  Toxicology       Date:  1975       Impact factor: 4.221

9.  Changes in the number of astrocytes and microglia in the thalamus of the monkey Macaca fascicularis following long-term subclinical methylmercury exposure.

Authors:  J S Charleston; R L Body; R P Bolender; N K Mottet; M E Vahter; T M Burbacher
Journal:  Neurotoxicology       Date:  1996       Impact factor: 4.294

Review 10.  Mercury and monomethylmercury: present and future concerns.

Authors:  W F Fitzgerald; T W Clarkson
Journal:  Environ Health Perspect       Date:  1991-12       Impact factor: 9.031

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  156 in total

Review 1.  The role of the placenta in fetal exposure to heavy metals.

Authors:  Claudia Gundacker; Markus Hengstschläger
Journal:  Wien Med Wochenschr       Date:  2012-05

2.  Glutathione complex formation with mercury(II) in aqueous solution at physiological pH.

Authors:  Vicky Mah; Farideh Jalilehvand
Journal:  Chem Res Toxicol       Date:  2010-10-12       Impact factor: 3.739

3.  Ca2+ entry pathways in mouse spinal motor neurons in culture following in vitro exposure to methylmercury.

Authors:  Gunasekaran Ramanathan; William D Atchison
Journal:  Neurotoxicology       Date:  2011-08-02       Impact factor: 4.294

4.  Synthesis, structure, and reactivity of two-coordinate mercury alkyl compounds with sulfur ligands: relevance to mercury detoxification.

Authors:  Jonathan G Melnick; Kevin Yurkerwich; Gerard Parkin
Journal:  Inorg Chem       Date:  2009-07-20       Impact factor: 5.165

5.  Relationship of methyl mercury accumulation with lipid and weight in two river cat fish species, Wallagoo attu and Mystus aor, from West Bengal, India.

Authors:  Moumita Pal; Mahua Ghosh
Journal:  Environ Monit Assess       Date:  2012-01-27       Impact factor: 2.513

6.  Exposure profiles of mercury in human hair at a terai belt of North India.

Authors:  Amit Masih; Ajay Taneja; Raj Singhvi
Journal:  Environ Geochem Health       Date:  2015-04-03       Impact factor: 4.609

7.  Gestational exposure to methylmercury and selenium: effects on a spatial discrimination reversal in adulthood.

Authors:  Miranda N Reed; Elliott M Paletz; M Christopher Newland
Journal:  Neurotoxicology       Date:  2006-04-15       Impact factor: 4.294

Review 8.  Neurobehavioural and molecular changes induced by methylmercury exposure during development.

Authors:  Carolina Johansson; Anna F Castoldi; Natalia Onishchenko; Luigi Manzo; Marie Vahter; Sandra Ceccatelli
Journal:  Neurotox Res       Date:  2007-04       Impact factor: 3.911

Review 9.  Neurotoxicity of organomercurial compounds.

Authors:  Coral Sanfeliu; Jordi Sebastià; Rosa Cristòfol; Eduard Rodríguez-Farré
Journal:  Neurotox Res       Date:  2003       Impact factor: 3.911

10.  Relationship of estimated dietary intake of n-3 polyunsaturated fatty acids from fish with peripheral nerve function after adjusting for mercury exposure.

Authors:  Yi Wang; Jaclyn M Goodrich; Robert Werner; Brenda Gillespie; Niladri Basu; Alfred Franzblau
Journal:  Sci Total Environ       Date:  2013-03-26       Impact factor: 7.963

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