| Literature DB >> 11832235 |
Abstract
Neuronal apoptosis is a cardinal feature of late-onset neurodegenerative disorders such as Alzheimer's and Huntington's disease. Biochemical and cell biological studies point to a role for Hip1 and Hippi in caspase-8 activation and the initiation of apoptosis during the pathogenesis of Huntington's disease.Entities:
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Year: 2002 PMID: 11832235 DOI: 10.1016/s1534-5807(02)00121-1
Source DB: PubMed Journal: Dev Cell ISSN: 1534-5807 Impact factor: 12.270